化工学报2025，Vol.76Issue(3)：909-921,13.DOI:10.11949/0438-1157.20240830
生物法制备衣康酸研究进展
Advance on the preparation of itaconic acid by biological method
摘要
Abstract
Itaconic acid(IA)is one of the important raw materials in chemical production and one of the most promising high-value-added platform compounds.It can replace petroleum-based acrylic acid and methacrylic acid.Furthermore,itaconic acid possesses significant pharmacological properties,such as anti-inflammatory,antiviral,and immune regulation functions,positioning it as a prospective drug candidate molecule in pharmaceutical research and development.In light of both domestic and international research advancements,this article provides a comprehensive review of the biosynthetic pathways and recent progress in the biosynthesis of itaconic acid.Additionally,it addresses strategies for enhancing itaconic acid production and offers an outlook on prospective research directions in the realm of itaconic acid.关键词
衣康酸/生物工程/工艺优化/生物催化/合成生物学Key words
itaconic acid/biological engineering/process optimization/biocatalysis/synthetic biology分类
生物学引用本文复制引用
张静,元跃,刘艳梅,王智文,陈涛..生物法制备衣康酸研究进展[J].化工学报,2025,76(3):909-921,13.基金项目
国家重点研发计划项目(2018YFA0900204) （2018YFA0900204）
