南京农业大学学报2025，Vol.48Issue(2)：249-262,14.DOI:10.7685/jnau.202404049
大豆致敏原表位与降敏加工:现状与未来
Allergenic epitope and desensitization processing of soybean:current status and future features
摘要
Abstract
Soybean is a traditional high-quality source of plant protein in China,however,soybean allergy restricts it nutritional and safety quality.The specific structure of soybean protein(allergen epitopes)is attributed to allergenicity,and the recognition and localization of epitopes are the key issues to exploring the mechanism of soybean allergies and targeted development and processing of hypoallergenic soybean foods.It is also the core of establishing the"structure-activity"relationship of precise soybean desensitization technology.This paper reviewed the changes in the structure and epitopes of soybean allergens during processing and gastrointestinal digestion processes.It also explored the effects of soybean allergen on the small intestine environment and oral immune tolerance.This literature review aimed to provide reference for the establishment of the"structure-activity"relationship in hypoallergenic soybean processing and the future development of soybean desensitization processing.关键词
大豆致敏原蛋白/致敏原表位/加工技术/胃肠道消化/蛋白摄入/口服耐受Key words
soybean allergenic protein/allergen epitope/processing technology/gastrointestinal digestion/protein uptake/oral tolerance分类
轻工纺织引用本文复制引用
芮昕,郭欣冉..大豆致敏原表位与降敏加工:现状与未来[J].南京农业大学学报,2025,48(2):249-262,14.基金项目
国家自然科学基金项目(32372440) （32372440）
