中国伤残医学2025，Vol.33Issue(5)：31-34,45,5.DOI:10.13214/j.cnki.cjotadm.2025.001.008
胺碘酮联合门冬氨酸钾镁对急诊急性心肌梗死并发恶性心律失常患者救治效果及心肌损伤指标的影响
Effects of Amiodarone Combined with Potassium Magnesium Aspartate on the Therapeutic Effect and Myocardial Injury Indexes of Patients with Acute Myocardial Infarction Complicated with Malignant Arrhythmia
谢华磊 1王云鹏 2田之雷 3郭旖旎4
作者信息
- 1. 山东第一医科大学附属聊城二院急诊,山东 聊城 252000
- 2. 山东省聊城市第二人民医院心内科一病区,山东 聊城 252000
- 3. 山东省聊城市第二人民医院急诊科,山东 聊城 252000
- 4. 山东省聊城市第二人民医院血液风湿科,山东 聊城 252000
- 折叠
摘要
Abstract
Objective:To explore the effects of Amiodarone combined with Potassium Magnesium Aspartate on the therapeutic effect and myocardial injury indexes of patients with acute myocardial infarction(AMI)complicated with malignant arrhythmia.Methods:The clinical data of 108 patients with AMI complicated with malignant arrhythmia admitted to the emergency department of Liaocheng Second Hospital Affiliated to Shandong First Medical University from October 2021 to October 2023 were retrospectively analyzed.According to different treatment methods,they were divided into control group and study group,with 54 cases in each group.The control group was treated with Amiodarone,and the study group was treated with Amiodarone combined with Potassium Magnesium Aspartate.Both groups were treated for 4 weeks.The clinical efficacy,myocardial injury indexes,cardiac function indexes and the occurrence of adverse reactions were compared between the two groups.Results:The total effective rate of the study group was 94.44%,which was higher than 81.48%of the control group,with statistical significance(P<0.05).After treatment,the serum creatine kinase isoenzyme,cardiac troponin I,lactate dehydrogenase and muscle red egg white water in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).After treatment,left ventricular ejection fraction in the study group was higher than that in the control group,and left ventricular end-diastolic diameter and left ventricular end-systolic diameter were shorter than that in the control group,the differences were statistically significant(P<0.05).The incidence of adverse reactions in the study group was 11.11%,which was higher than 7.41%in the control group,but there was no significant difference between the two groups(P<0.05).Conclusion:Amiodarone combined with Potassium Magnesium Aspartate has obvious clinical efficacy in the treatment of AMI patients with malignant arrhythmia,and can effectively improve myocardial injury indexes and cardiac function,with high safety.关键词
急性心肌梗死/恶性心律失常/胺碘酮/门冬氨酸钾镁/救治效果/心肌损伤/心功能/不良反应Key words
Acute myocardial infarction/Malignant arrhythmia/Amiodarone/Potassium Magnesium Aspartate/Treatment effect/Myocardial injury/Heart function/Adverse reactions分类
临床医学引用本文复制引用
谢华磊,王云鹏,田之雷,郭旖旎..胺碘酮联合门冬氨酸钾镁对急诊急性心肌梗死并发恶性心律失常患者救治效果及心肌损伤指标的影响[J].中国伤残医学,2025,33(5):31-34,45,5.
