肿瘤预防与治疗2025，Vol.38Issue(3)：224-230,7.DOI:10.3969/j.issn.1674-0904.2025.03.007
锥形束CT(CBCT)在中下段食管癌患者放射治疗中的价值分析
Evaluation of Cone Beam CT(CBCT)in Radiotherapy for Patients with Middle and Lower Esophageal Cancer
摘要
Abstract
Objective:To investigate the application value of cone beam computed tomography(CBCT)in radiotherapy for middle and lower esophageal cancer and to provide evidence for clinical practice.Methods:A total of 101 patients with middle and lower esophageal cancer were retro-spectively enrolled.During positioning,a crossline was marked on the body surface,and patients were instructed to cross their arms and place their elbows in front of their fore-head,secured with a body membrane.CBCT images were acquired at the first treatment session and weekly thereafter.These images were matched with the planning CT images to determine setup errors in the left-right(X-axis),superior-inferior(Y-axis),and anterior-posterior(Z-axis)directions,as well as the treatment couch rotation angle θ.The setup errors were ana-lyzed,and the planning target volume(PTV)margins were calculated using a standard formula.Results:A total of 224 CBCT images were obtained.The overall setup errors in the X,Y,and Z directions and the rotation angle θ were(-0.02±0.20)cm,(0.05±0.25)cm,(0.03±0.16)cm,and(-0.03±0.64)°,respectively.The differences in setup errors among the X,Y,and Z directions were statistically significant(F=7.537,P=0.001).Pairwise comparisons revealed sta-tistically significant differences between the X and Y directions(P＜0.001)and between the X and Z directions(P=0.013).The calculated PTV margins in the X,Y,and Z directions were 0.46 cm,0.63 cm,and 0.40 cm,respectively.Compared with the first week,the mean setup error in the X direction increased by 0.05 cm in the fourth week,while the mean setup error in the Z direction decreased by 0.04 cm in the fifth week,both of which were statistically significant(P=0.024 and P=0.016,respectively).Conclusion:For patients with middle and lower esophageal cancer,the application of CBCT enables accurate analysis of setup errors,standardizes PTV margins effectively,guides therapists in patient setup,reduces setup errors,and improves the precision of radiotherapy.关键词
中下段食管癌/锥形束CT/调强放射治疗/摆位误差/外扩范围Key words
Middle and lower esophageal carcinoma/Cone beam CT/Intensity modulated radiation therapy/Setup errors/Margin of PTV分类
医药卫生引用本文复制引用
朱均强,孙绍涵,班卫华,苏善宁,吕伟,庞林..锥形束CT(CBCT)在中下段食管癌患者放射治疗中的价值分析[J].肿瘤预防与治疗,2025,38(3):224-230,7.基金项目
广西壮族自治区卫健委自筹经费科研课题(编号:Z20180443) （编号:Z20180443）
玉林市科学研究与技术开发计划项目(编号:[玉市科]20220609) This study was supported by grants from Science and Technology Department of Guangxi Zhuang Autono-mous Region(No.Z20180443)and Science and Technology Bureau of Yulin,Guangxi(No.20220609). （编号:[玉市科]20220609）
