新发传染病电子杂志2025，Vol.10Issue(1)：17-21,5.DOI:10.19871/j.cnki.xfcrbzz.2025.01.004
CT在肺癌与肺癌合并肺结核鉴别诊断中的应用价值
Application value of CT in the differential diagnosis of lung cancer and lung cancer with tuberculosis
摘要
Abstract
Objective To explore the value of CT in the differential diagnosis of lung cancer and lung cancer combined with tuberculosis by comparing and analyzing the typical CT signs.Method The clinical and imaging data of 100 cases of lung cancer(lung cancer group)and 71 cases of lung cancer complicated with tuberculosis(lung cancer complicated with tuberculosis group)were collected from Beijing Chest Hospital,Capital Medical University retrospectively,All patients underwent plain chest CT scan and contrast-enhanced CT scan.70 cases of simple lung cancer and 51 cases of lung cancer combined with pulmonary tuberculosis patients admitted from June 2019 to January 2023 were used as the training set,and 30 cases of simple lung cancer and 20 cases of lung cancer combined with pulmonary tuberculosis patients admitted from May 2017 to January 2019 were used as the testing set.Compare the differences in age,gender and CT imaging features between two groups of patients,and select the features with statistically significant differences.The differential diagnosis model was constructed by multi-factor logistic regression and tested on an independent test set.The model performance was evaluated by receiver operator characteristic curve(ROC curve).Result There were significant differences in age,gender,vacuole sign,vascular cluster sign,pleural effusion,pleural thickening,enhancement pattern,bronchiectasis and stenosis between the two groups(P＜0.05).The differential model constructed according to these features performed well,with the area under ROC curve of 0.901 in the training set and 0.871 in the test set.Conclusion Patients with lung cancer and lung cancer combined with tuberculosis have overlapping CT signs,which makes it easy to confuse the two diseases.The established differential diagnosis model is good and helpful to distinguish the two diseases.关键词
肺癌/肺癌合并肺结核/体层摄影术/X线/鉴别诊断Key words
Lung cancer/Lung cancer with tuberculosis/Body section radiography/X-ray/Differential diagnosis分类
医药卫生引用本文复制引用
温立旻,李晔,李恒星,林伟,侯代伦..CT在肺癌与肺癌合并肺结核鉴别诊断中的应用价值[J].新发传染病电子杂志,2025,10(1):17-21,5.基金项目
1.黑龙江省卫生健康委科研课题(20230909010416) （20230909010416）
2.北京市医院管理中心临床医学发展专项"扬帆"计划(XMLX202146) （XMLX202146）
