新发传染病电子杂志2025，Vol.10Issue(1)：22-26,5.DOI:10.19871/j.cnki.xfcrbzz.2025.01.005
广西地区585例耐多药/利福平耐药结核患者的治疗转归影响因素分析
Analysis of factors affecting treatment outcomes in 585 multidrug-resistant/rifampicin-resistant tuberculosis patients in Guangxi area
摘要
Abstract
Objective This study aims to analyze the factors influencing the treatment outcomes of multidrug-resistant/rifampicin-resistant tuberculosis(MDR/RR-TB)patients in Guangxi from 2019 to 2021,providing data support for the treatment and prevention of drug-resistant tuberculosis.Method A retrospective study was conducted to collect clinical data and treatment outcomes for 585 MDR/RR-TB patients who visited a tuberculosis hospital in Guangxi during the specified period.The analysis focused on the impact of various factors on the treatment outcomes of these patients.Result The overall treatment success rate for MDR/RR-TB patients was 53.33%,with annual rates of 51.02%,53.30%,and 54.98%from 2019 to 2021,respectively.The main factors influencing treatment outcomes included gender,age,population classification,treatment classification,adverse drug reactions,and the presence of comorbidities such as diabetes and lung disease(P＜0.05),male patients,those over 24 years old,patients with adverse drug reactions,and those with diabetes were more likely to have poor treatment outcomes(P＜0.05).Conclusion The treatment of MDR/RR-TB in Guangxi has shown promising results,with an increasing treatment success rate from 2019 to 2021.Future treatment and supervision efforts should prioritize male patients,the elderly,those experiencing adverse drug reactions,and patients with diabetes,while also enhancing the monitoring of adverse drug reactions to improve the treatment success rate for drug-resistant tuberculosis.关键词
利福平耐药结核/耐多药结核/影响因素/成功治疗Key words
Rifampicin-resistant tuberculosis/Multidrug-resistant tuberculosis/Influencing factors/Successful treatment分类
医药卫生引用本文复制引用
吕柳英,梁月新,张凯,曾慧频,黄丽花,黄俊理,刘爱梅..广西地区585例耐多药/利福平耐药结核患者的治疗转归影响因素分析[J].新发传染病电子杂志,2025,10(1):22-26,5.基金项目
1.广西科技重大专项(桂科AA22096027) （桂科AA22096027）
2.广西医疗卫生适宜技术开发与推广应用项目(S2022041) （S2022041）
