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基于网络药理学浅谈补脾健胃汤治疗羔羊腹泻的作用机理

贾燕 李华坤 杨彬偲 陈兰

现代畜牧科技Issue(3):18-20,3.
现代畜牧科技Issue(3):18-20,3.DOI:10.19369/j.cnki.2095-9737.2025.03.005

基于网络药理学浅谈补脾健胃汤治疗羔羊腹泻的作用机理

A Brief Discussion on the Mechanism of Bupijianwei Decoction in Treating Lamb Diarrhea Based on Network Pharmacology

贾燕 1李华坤 1杨彬偲 1陈兰1

作者信息

  • 1. 徐州生物工程职业技术学院,江苏 徐州 221006
  • 折叠

摘要

Abstract

To analyze the mechanism of Bupijianwei Decoction in the treatment of lamb diarrhea.Network pharmacology was used to analyze how to treat lamb diarrhea with spleen and stomach decoction.Bupijianwei Decoction contained 19 active chemical components and 174 drug targets,and a total of 893 targets related to lamb diarrhea were collected,among which PTGS2,TNF,NOS2,AKT1,IL6,CASP3,and PTGS1 were the key targets,and berberine,epiberberine,quercetin,kaempferol and berberine methyl contained more related gene targets.The pharmacological mechanism of action of Bupijianwei Decoction on lamb diarrhea is revealed.

关键词

腹泻/药理学/活性/靶基因

Key words

diarrhea/pharmacology/activity/target genes

分类

畜牧业

引用本文复制引用

贾燕,李华坤,杨彬偲,陈兰..基于网络药理学浅谈补脾健胃汤治疗羔羊腹泻的作用机理[J].现代畜牧科技,2025,(3):18-20,3.

基金项目

江苏现代农业(肉羊)产业技术体系项目(JATS[2023]053) (肉羊)

规模化羊场沙门菌病防控技术研究与应用(KC23136) (KC23136)

现代畜牧科技

2095-9737

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