中国感染控制杂志2025，Vol.24Issue(3)：316-322,7.DOI:10.12138/j.issn.1671-9638.20256933
254 nm连续紫外线与脉冲紫外激光物体表面消毒研究
Surface disinfection efficacy of 254 nm continuous ultraviolet and pulsed ultraviolet laser
摘要
Abstract
Objective To compare and analyze the germicidal efficacy of continuous ultraviolet and pulsed ultravio-let(UV)lasers on pathogenic microorganisms.Methods Spore slides of Escherichia coli and Bacillus atrophaeus were irradiated using a 254 nm ultraviolet mercury lamp and UV laser.The carrier quantitative germicidal test was conducted to determine the disinfection efficacy at different irradiation doses.Results When the irradiation dose of the ultraviolet mercury lamp was 245.52 mJ/cm2,the logarithmic killing values of Escherichia coli and Bacillus atro-phaeus spores were 5.00 and 2.92,respectively,and the mean logarithmic killing doses were 49.10 and 84.08 mJ/cm2,respectively;When the UV laser irradiation doses were 208.39 and 206.80 mJ/cm2,the logarithmic killing values for the two microorganisms were 6.29 and 3.32,respectively,and the mean logarithmic killing doses were 33.13 and 62.29 mJ/cm2,respectively.Conclusion Compared with continuous UV radiation,pulsed UV laser has stron-ger penetration ability,better killing efficacy on pathogenic microorganisms at the same radiation dose,and can con-duct targeted disinfection and sterilization on the surface of objects directionally.关键词
紫外线/脉冲紫外激光/连接紫外线/消毒/灭菌/杀灭对数值Key words
ultraviolet/pulsed ultraviolet laser/continuous ultraviolet/disinfection/sterilization/logarithmic killing value分类
医药卫生引用本文复制引用
赵洁,赵蕾,商怡然,吴金辉,衣颖,邓橙,祁建城,张宗兴..254 nm连续紫外线与脉冲紫外激光物体表面消毒研究[J].中国感染控制杂志,2025,24(3):316-322,7.基金项目
国家重点研发计划课题(2021YFC2600304) （2021YFC2600304）
