中国感染控制杂志2025，Vol.24Issue(3)：417-421,5.DOI:10.12138/j.issn.1671-9638.20255457
259例心脏移植术后受者感染状况分析
Characteristics of infection in 259 recipients after heart transplantation
摘要
Abstract
Objective To understand the epidemiological characteristics of infection in recipients after heart trans-plantation,and provide references for the prevention and control of postoperative infections.Methods Clinical data of 259 heart transplant recipients in a hospital from April 2018 to December 2023 were collected for epidemiological analysis.Results Among 259 heart transplant patients,55 developed 68 episodes of infection during the first hospi-talization after surgery,the incidence of infection was 21.24％,and the case incidence of infection was 26.25％.The main infection sites were lower respiratory tract(n=30,44.12％),blood system(n=21,30.88％),and uri-nary system(n=8,11.76％).Sixty-eight episodes of infections occurred primarily within 10 days after surgery(n=37,54.41％),fo-llowed by within 11-20 days(n=14,20.59％).A total of 74 pathogens were detected from the infected site,mainly Gram-negative bacteria(n=37,50.00％),followed by fungi(n=19,25.68％),Gram-posi-tive bacteria(n=12,16.22％),viruses(n=6,8.11％).The multidrug-resistant rates of Klebsiella pneumoniae,Acinetobacter baumannii,Pseudomonas aeruginosa,and Enterococcus spp.were relatively high(57.1％-100％).During the period from discharge to one year after surgery,31 patients developed 39 episodes of infection,mainly lower respiratory tract infection(n=29,74.36％).Conclusion Heart transplant recipients have a high incidence of postoperative infection,with lower respiratory tract being the main infection site and with a high resistance rate of pathogen.The critical period for infection prevention and control is within 10 days after surgery.关键词
心脏移植/感染/病原菌/耐药性Key words
heart transplantation/infection/pathogen/drug resistance分类
医药卫生引用本文复制引用
宋亚佩,吴艳,黄白艳,郭兵兵..259例心脏移植术后受者感染状况分析[J].中国感染控制杂志,2025,24(3):417-421,5.基金项目
河南省科技发展计划项目(242102310224) （242102310224）
郑州市医学科技攻关计划项目(ZZYK2024064) （ZZYK2024064）
