中国实验动物学报2025，Vol.33Issue(2)：275-287,13.DOI:10.3969/j.issn.1005-4847.2025.02.013
模式生物斑马鱼作为抑郁模型的研究进展
Progress of research into the zebrafish(Danio rerio)depression model
摘要
Abstract
The zebrafish is characterized by its rapid reproductive cycle,transparent embryonic body in the early developmental stages,high genetic and physiological homology with humans,and low breeding costs.These advantages make it a valuable tool that complements mammalian models of depression.The zebrafish has emerged as a promising model organism for studying mental illnesses owing to its unique biological characteristics and the diverse method available for establishing depression models using this species.This article aims to provide a comprehensive review of zebrafish depression model establishment method,evaluation criteria,advantages,and limitations.关键词
斑马鱼/抑郁症/疾病动物模型Key words
zebrafish/depression/animal model of disease分类
生物科学引用本文复制引用
郭碧玉,杨惠栾,陈依凡,杨晓密,姚政,毛羽..模式生物斑马鱼作为抑郁模型的研究进展[J].中国实验动物学报,2025,33(2):275-287,13.基金项目
云南省科技厅中医基础研究联合专项(202001AZ0001-040). Funded by Department of Science and Technology of Yunnan Province Joint Project of Basic Research of Traditional Chinese Medicine(202001AZ0001-040). （202001AZ0001-040）
