巴楚医学2025，Vol.8Issue(1)：23-29,7.DOI:10.3969/j.issn.2096-6113.2025.01.005
宜昌市182例毒蘑菇中毒患者的临床特征分析
Clinical Characterization of 182 Patients with Poisonous Mushroom Poisoning in Yichang City
摘要
Abstract
Objective:To analyze the epidemiological characteristics,clinical features,and treatment outcomes of patients with mushroom poisoning in Yichang City,providing a reference for improving the diagnosis and treatment effects of patients with mushroom poisoning.Methods:A retrospective analysis was conducted on 182 patients with mushroom poisoning who were treated at Yichang Central People's Hospital from May 2014 to May 2024.General clinical data of all included patients were collected and analyzed,and the epidemiological characteristics,clinical features,and treatment outcomes were further analyzed.Results:The onset of patients was mainly concentrated in the summer and autumn seasons,with an age range of 35 to 65 years old,and farmers were the main group affected.The poisoning patients mainly presented with gastrointestinal symptoms,including nausea/vomiting(86.26％),abdominal pain(59.89％),and diarrhea(37.91％).The clinical classification of patients was mainly acute liver damage type(48.90％),and the proportion of severe patients was 39.56％.Patients had abnormal changes in myocardial enzymes,liver and kidney function,and electrocardiograms to varying degrees.Among the 147 patients who received hospital treatment,45 severe cases of liver and kidney failure underwent blood purification therapy,and the patients'alanine aminotransferase,creatine kinase isoenzyme-MB and prothrombin activity showed significant improvement compared to before treatment.Conclusion:Mushroom poisoning can cause damage to multiple organs such as the liver,kidneys,and heart.Generally,poisoning symptoms can be improved through medication treatment.For severe patients with combined liver and kidney failure,after blood purification treatment,the related indicators of liver and kidney function significantly improved.To reduce the risk of mushroom poisoning,it is necessary to strengthen the popularization of scientific education and the construction of foodborne disease surveillance networks.关键词
毒蘑菇/蘑菇中毒/血液净化治疗Key words
poisonous mushrooms/mushroom poisoning/blood purification therapy分类
临床医学引用本文复制引用
郭建强,郑婷婷,张恒,张蓉..宜昌市182例毒蘑菇中毒患者的临床特征分析[J].巴楚医学,2025,8(1):23-29,7.基金项目
湖北省自然科学基金项目(2024AFB845) （2024AFB845）
