巴楚医学2025，Vol.8Issue(1)：49-53,5.DOI:10.3969/j.issn.2096-6113.2025.01.009
大致正常心电图中Tp-Te间期预测冠状动脉重度狭窄的临床研究
Clinical Study on the Prediction of Severe Coronary Artery Stenosis by Tp-Te Interval in Approximately Normal Electrocardiograms
摘要
Abstract
Objective:By analyzing the changes in the T wave peak-to-end interval(Tp-Te interval)in approximately normal electrocardiograms,this study explores whether the Tp-Te interval can be used to predict severe coronary artery stenosis.Methods:A total of 663 patients who underwent coronary CT angiography at Yichang Central People's Hospital between January 2020 and May 2024 were collected.Among them,patients with severe stenosis(≥90％narrowing)of the left anterior descending artery were assigned to the case group(n=146),while patients with no stenosis and no other abnormalities were assigned to the control group(n=517).ECG records of both groups were collected,and the Tp-Te intervals were measured.Logistic regression model was used to plot the receiver operating characteristic(ROC)curve,calculate the area under the curve(AUC),and draw the Youden index curve to determine the threshold,sensitivity,and specificity of the Tp-Te interval for diagnosing severe coronary artery stenosis.Results:Compared with the control group,the Tp-Te intervals in V1[(82.91±18.73)ms vs(72.31±15.22)ms],V2[(90.48±16.86)ms vs(84.23±13.45)ms],V3[(90.13±16.04)ms vs(83.11±14.79)ms],and V4[(88.86±15.03)ms vs(71.12±13.94)ms]were significantly increased in the case group(all P＜0.001).The AUC values for V1 to V4 and the combined prediction were 0.691,0.582,0.573,0.714,and 0.633,respectively.At a Tp-Te interval of 79.5 ms in V4,the sensitivity for prediction was 74.66％,and the specificity was 77.40％,representing the optimal balance point for clinical prediction at 52.06％.Conclusion:The Tp-Te interval can predict severe coronary artery stenosis,with the largest effect size and highest predictive efficacy in V4.The threshold for the Tp-Te interval is 79.5 ms.关键词
心电图/冠状动脉狭窄/Tp-Te间期Key words
electrocardiogram/coronary artery stenosis/Tp-Te interval分类
医药卫生引用本文复制引用
杨艳丽,李颖,习诗良..大致正常心电图中Tp-Te间期预测冠状动脉重度狭窄的临床研究[J].巴楚医学,2025,8(1):49-53,5.基金项目
中央引导地方科技发展专项基金项目(2022BGE237) （2022BGE237）
三峡大学科学基金项目(2022kj008) （2022kj008）
三峡大学科学专项基金项目(2023kjzx001) （2023kjzx001）
