巴楚医学2025，Vol.8Issue(1)：82-89,8.DOI:10.3969/j.issn.2096-6113.2025.01.015
1990-2021年中国结直肠癌疾病负担和危险因素分析
Analysis of Disease Burden and Risk Factors for Colorectal Cancer in China from 1990 to 2021
摘要
Abstract
Objective:To investigate the disease burden of colorectal cancer(CRC)in China.Methods:The China CRC data from the Global Burden of Disease database(2021)was downloaded.We analyzed the incidence,prevalence,mortality,disability-adjusted life years(DALYs),years of life lost due to premature mortality(YLLs),years lived with disability(YLDs),and risk factors associated with CRC.Results:In 2021,the number of CRC cases,prevalence,and deaths in China were 658 300,3 605 700,and 275 100,respectively;the age-standardized incidence rate,prevalence rate,and mortality rate were 31.44/100 000,168.62/100 000,and 13.64/100 000.Compared with 1990,there was a significant increase in the age-standardized incidence and prevalence rates(both P＜0.05),while the age-standardized mortality rate decreased significantly(P＜0.05).Additionally,DALYs,YLLs,and YLDs showed an increasing trend from 1990 to 2021(all P＜0.05),increasing by 92.09％,86.45％,and 381.23％,respectively.Notably,the age groups 65～69 and 70～74 had the highest incidence of CRC,with the highest disease burden in the 65～69 age group(DALYs,YLLs,and YLDs).In 2021,the top ten risk factors for CRC in China were insufficient dairy intake,insufficient whole grain intake,excessive red meat consumption,high body mass index,insufficient calcium intake,smoking,excessive alcohol consumption,high fasting plasma glucose,low physical activity,and excessive processed meat intake.Conclusion:From 1990 to 2021,the incidence and prevalence of CRC in China significantly increased,while the mortality rate decreased,with the highest disease burden in the 65～69 age group.Therefore,this age group should be the focus of CRC screening and prevention.关键词
结直肠癌/疾病负担/危险因素Key words
colorectal cancer(CRC)/disease burden/risk factors分类
医药卫生引用本文复制引用
李子锋,常彩云,席祖洋,易文,曾晓倩..1990-2021年中国结直肠癌疾病负担和危险因素分析[J].巴楚医学,2025,8(1):82-89,8.基金项目
湖北省中医药科研基金项目(ZY2021M011) （ZY2021M011）
