巴楚医学2025，Vol.8Issue(1)：124-128,5.DOI:10.3969/j.issn.2096-6113.2025.01.022
半乳糖凝集素-3在2型糖尿病及其并发症中的作用机制研究进展
Research Progress on the Mechanism of Galectin-3 in Type 2 Diabetes and Its Complications
摘要
Abstract
Due to the continuous progression of population aging and changes in residents'lifestyle and dietary habits in China,the incidence of type 2 diabetes mellitus(T2DM)is increasing year by year.The common complications of T2DM include diabetic nephropathy,neuropathy,retinopathy,cardiomyopathy,and vascular disease.The progression of T2DM and its complications has a severe impact on patients'quality of life and prognosis.Galectin-3(Gal-3)is a potent pro-inflammatory factor that plays a significant role in the activation,chemotaxis,and cytokine release of inflammatory cells,which is closely related to abnormal glucose metabolism and related target organ damage.This article reviews the mechanism of action of Gal-3 in T2DM,with the hope of providing new monitoring indicators and therapeutic targets for the prevention and treatment of T2DM and its complications.关键词
半乳糖凝集素-3/2型糖尿病/糖尿病并发症Key words
galectin-3(Gal-3)/type 2 diabetes mellitus(T2DM)/diabetes complications分类
临床医学引用本文复制引用
何婷..半乳糖凝集素-3在2型糖尿病及其并发症中的作用机制研究进展[J].巴楚医学,2025,8(1):124-128,5.基金项目
湖北省卫生健康委员会联合基金项目(WJ2019H548) （WJ2019H548）
