重庆医学2025,Vol.54Issue(3):620-624,5.DOI:10.3969/j.issn.1671-8348.2025.03.011
Bias Plan剂量叠加法对左乳腺癌术后放疗计划的影响研究
Impact of Bias Plan dose superposition on postoperative radiotherapy planning for left breast cancer
摘要
Abstract
Objective To investigate the dosimetry effect of Sum Plan and Bias Plan in the Monaco planning system for the addition of compensatory agents after left breast cancer surgery.Methods Twenty-nine patients with radical left mastectomy who received radiotherapy in this hospital from March 2023 to Feb-ruary 2024 were selected as the study objects.Based on the Monaco planning system and under the same opti-mal conditions,Sum Plan and Bias Plan were used to design the second-course plan based on the first-course plan.Sum Plan C1 and Bias Plan C2 were generated to compare the dosimetry differences of intensity modula-ted radiotherapy(IMRT)plans under the two dosimetric superposition methods.Results Compared with Sum Plan C1,the conformability index(CI)in the planned target area(PTV)of Bias Plan C2 was worse,the homogeneity index(HI)was better,and the mean cardiac dose(Dmean),V5,V10,V30,V40 in the organs at risk were better than that of Sum Plan C1.The Dmean,V5,V20 and contralateral V5 in the affected lung were lower,while the V5,V10,V15,V20,V25,V30 in the normal tissue were lower,while V35 was higher,and the number of subfields and machine hops were more,the difference was statistically significant(P<0.05).Conclusion Bias Plan dose overlay method was proposed in the design of segmental radiotherapy with compensator after left breast cancer surgery.关键词
Sum Plan/Bias Plan/乳腺癌术后/剂量学/MonacoKey words
Sum Plan/Bias Plan/postoperative breast cancer/dosimetry/Monaco分类
医药卫生引用本文复制引用
刘攀,董建伟,赵文龙,刘景,朱彤..Bias Plan剂量叠加法对左乳腺癌术后放疗计划的影响研究[J].重庆医学,2025,54(3):620-624,5.基金项目
江西省科学技术厅科技计划项目(20161BBG70036) (20161BBG70036)
江西省吉安市科技局科技计划项目(20233-043504). (20233-043504)