南方医科大学学报2025，Vol.45Issue(3)：443-452,10.DOI:10.12122/j.issn.1673-4254.2025.03.01
北京地区近10年骨质疏松症流行病学调查:一项单中心30599例汉族人群双能X线吸收法骨密度检查结果分析
Epidemiological survey of osteoporosis in Beijing over the past decade:a single-center analysis of dual-energy X-ray absorptiometry scans from 30 599 individuals
摘要
Abstract
Objective To analyze bone mass distribution and the factors affecting bone mass in a general Chinese Han cohort undergoing physical examinations at our center.Methods We retrospectively collected the data of bone mineral density(BMD)measurements from 30 599 healthy Han Chinese adults(age≥20 years)who underwent dual-energy X-ray absorptiometry scans at our hospital from July,2013 to July,2023.Basic parameters including height,body weight,and gender were recorded,and descriptive statistics and correlation analyses were performed using R software.Results In this cohort,the male individuals had a mean peak BMD of 1.00±0.12 g/cm2 in the lumbar vertebrae,0.94±0.14 g/cm2 in the femoral neck,and 0.99±0.13 g/cm2 in the total hip,significantly higher than the values in the female individuals[0.99±0.12 g/cm2 in the lumbar vertebrae(P=0.022),0.79±0.11 g/cm2 in the femoral neck(P<0.001),and 0.88±0.11 g/cm2 in the total hip(P<0.001)].In the overall cohort,the BMD values of the lumbar spine and femur decreased with age after reaching their peak levels.There was a positive correlation between BMD value and body mass index(BMI)in both male and female individuals.The 2013-2014 period recorded the lowest BMD values in the lumbar,hip,and femoral neck,which tended to increase steadily in the following years(2015-2023).Conclusion Our data suggest that the BMD values vary among different populations,and future multi-center studies using more accurate BMD detection technology are warranted to capture the variation patterns of BMD with demographic characteristics of specific populations.关键词
骨密度/骨质疏松/双能X射线吸收/流行病学Key words
bone mineral density/osteoporosis/dual-energy X-ray/epidemiology引用本文复制引用
周莹,许王莉,李晓,张丹阳,吴立凡,王桂杉,母杰丹,崔成文,石秀秀,董继革,王瑜..北京地区近10年骨质疏松症流行病学调查:一项单中心30599例汉族人群双能X线吸收法骨密度检查结果分析[J].南方医科大学学报,2025,45(3):443-452,10.基金项目
国家重点研发项目(2023YFC3604905) （2023YFC3604905）
