分子影像学杂志2025，Vol.48Issue(3)：379-384,6.DOI:10.12122/j.issn.1674-4500.2025.03.19
门控心肌灌注显像室壁运动在心血管疾病中的应用进展
Research progress of wall motion in gated myocardial perfusionimaging in cardiovascular diseases
摘要
Abstract
Myocardial wall motion dysfunction represents a pivotal early pathophysiological mechanism underlying the structural and functional deterioration observed in various cardiovascular diseases,and it is strongly correlated with patient prognosis.Gated myocardial perfusion imaging is a cornerstone non-invasive imaging modality for evaluating myocardial ischemia and viability in patients with cardiovascular disorders.Utilizing advanced post-processing software,gated myocardial perfusion imaging enables the quantification of both global and regional left ventricular functional parameters.Recent advancements have significantly enhanced myocardial wall motion assessment.These include dedicated cardiac SPECT technology,optimized acquisition protocols,sophisticated image reconstruction algorithms,and the integration of artificial intelligence.This review examines the application value and research progress of gated myocardial perfusion imaging in cardiovascular diseases.It focuses on early diagnosis,risk stratification,and prognostic evaluation,particularly in ischemic heart disease.Additionally,the review critically analyzes the current limitations of G-MPI.It also explores future directions to provide novel insights for precise diagnosis and therapeutic management of cardiovascular diseases.关键词
心肌灌注显像/心血管疾病/室壁运动/发展趋势Key words
myocardial perfusion imaging/cardiovascular disease/wall motion/trends引用本文复制引用
任泰林,王若楠,吴秋岩,唐逊,李思进..门控心肌灌注显像室壁运动在心血管疾病中的应用进展[J].分子影像学杂志,2025,48(3):379-384,6.基金项目
国家自然科学基金(U22A6008) （U22A6008）
山西省基础研究自由探索类青年科学研究项目(202303021222344) Supported by National Natural Science Foundation of China(U22A6008) （202303021222344）
