赣南医科大学学报2025，Vol.45Issue(2)：177-182,6.DOI:10.3969/j.issn.1001-5779.2025.02.011
重复经颅磁刺激治疗青少年抑郁症非自杀性自伤行为的研究进展
Research progress of repetitive transcranial magnetic stimulation in the treatment of non-suicidal self-injury behavior in adolescents with depression
摘要
Abstract
Non-suicidal self-injury(NSSI),which is the act of intentionally harming one's own body without suicidal intent,is a common mental health problem among adolescents.In recent years,the incidence of NSSI has shown an increasing trend among adolescents with depression.Repetitive transcranial magnetic stimulation(rTMS),as a non-invasive neuromodulation technique,has been used to improve mood problems in patients with depression and anxiety disorders.More and more studies have shown that rTMS also improves NSSI behaviors in adolescents with depression with a high degree of safety and few side effects.This paper will synthesize the research literature from home and abroad in recent years,and review three aspects of the pathogenesis of adolescent NSSI,the relationship between adolescent depression and NSSI,and the treatment of adolescent depression NSSI behavior with rTMS.The results of the literature review show that rTMS combined with antidepressant medication can significantly improve the therapeutic efficacy of adolescent depression patients with NSSI behaviors,which not only enhances the antidepressant effect,but also effectively reduces the frequency and severity of self-injury.However,there is no consensus on the optimal stimulation modes and parameters for rTMS,and the specific mechanism of action of rTMS for the treatment of NSSI behaviors in adolescent depression remains to be further elucidated.Future studies could utilize advanced imaging techniques such as magnetic resonance imaging(MRI)and near-infrared spectroscopic imaging(NIRS)to pinpoint therapeutic targets,thus making rTMS treatment more personalized and providing patients with more precise and effective treatment.关键词
青少年抑郁症/非自杀性自伤/重复经颅磁刺激Key words
Adolescent depression/Non-suicidal self-injury/Repetitive transcranial magnetic stimulation分类
临床医学引用本文复制引用
杨侃,申璎,方锋峰,唐宏..重复经颅磁刺激治疗青少年抑郁症非自杀性自伤行为的研究进展[J].赣南医科大学学报,2025,45(2):177-182,6.基金项目
江西省哲学社会科学重点研究基地项目(23ZXSKJD51) （23ZXSKJD51）
