郑州大学学报（医学版）2025，Vol.60Issue(2)：282-285,4.DOI:10.13705/j.issn.1671-6825.2024.05.053
慢性阻塞性肺疾病患者饮食炎症指数与肌少症的关系
Relationship between dietary inflammatory index and sarcopenia in pa-tients with COPD
郑婧 1肖曼 1张琳 1刘红1
作者信息
- 1. 郑州大学第一附属医院呼吸与危重症医学科 郑州 450052
- 折叠
摘要
Abstract
Aim:To study the relationship between dietary inflammatory index(DII)and sarcopenia in patients with chronic obstructive pulmonary disease(COPD)based on the National Health and Nutrition Examination Survey(NHANES)database.Methods:Data on general information,DII,and sarcopenia were collected of COPD patients from NHANES during 1999-2006 and 2012-2018.COPD patients were categorized into Q1 to Q4 groups based on DII quartiles.Logistic regres-sion was used to analyze the relationship between DII and the risk of sarcopenia in COPD patients.Restricted cubic splines was used to analyze the dose-effect relationship between DII and the risk of sarcopenia.Results:The prevalence of sarcope-nia was 22.87％(121/529).Logistic analysis showed that after adjusting for age,race,gender,BMI,drinking,and physical activity,the risk of sarcopenia was higher in groups Q3 and Q4 compared with group Q1,and OR(95％CI)were 2.136(1.121-4.071),2.779(1.571-4.916).The risk of sarcopenia tended to increase in COPD patients in groups Q1,Q2,Q3,and Q4(P＜0.05).DII and sarcopenia showed dose-effect relationship when DII ≥2.51(Pnon-linearity=0.030).Conclu-sion:The risk of sarcopenia in COPD patients increases with the increase of DII when DII≥2.51.关键词
慢性阻塞性肺疾病/肌少症/饮食炎症指数/NHANES数据库Key words
chronic obstructive pulmonary disease/sarcopenia/dietary inflammatory index/NHANES database分类
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郑婧,肖曼,张琳,刘红..慢性阻塞性肺疾病患者饮食炎症指数与肌少症的关系[J].郑州大学学报（医学版）,2025,60(2):282-285,4.
