郑州大学学报（医学版）2025，Vol.60Issue(2)：216-220,5.DOI:10.13705/j.issn.1671-6825.2024.06.054
1990-2019年中国儿童青少年哮喘发病率与死亡率变化趋势分析
Trend of asthma incidence and mortality in Chinese children and adoles-cents from 1990 to 2019
摘要
Abstract
Aim:To analyze the trend of asthma incidence and mortality among children and adolescents aged 0-＜25 in China from 1990 to 2019.Methods:Data on asthma incidence and mortality among Chinese children and adolescents(aged 0-＜25)from 1990 to 2019 were obtained from the Global Burden of Disease Database.Joinpoint regression analy-sis and age-period-cohort model were used to for the analysis.Results:From 1990 to 2019,the average annual percent change(AAPC)in asthma incidence in different age groups(＜5,5-＜10,10-＜15,15-＜20,20-＜25 age groups)was 0.314％,-0.063％,-0.075％,-0.079％,and-0.160％,respectively.The AAPC for asthma mortality was-10.749％,-7.364％,-6.571％,-5.318％,and-8.275％,respectively.The age-period-cohort model revealed that asthma incidence and mortality decreased with increasing age.The period rate for incidence first declined and then in-creased,exhibiting a U-shaped trend(the lowest was in 2007),while the period rate for mortality consistently decreased(from 0.182 per 100 000 in 1990 to 0.021 per 100 000 in 2019).The cohort rate for incidence initially decreased and then increased(from 1.274 per 100 000 to 0.940 per 100 000 and then to 1.222 per 100 000),whereas the cohort rate for mor-tality steadily declined(from 3.471 per 100 000 to 0.374 per 100 000).Conclusion:From 1990 to 2019,asthma incidence and mortality among children and adolescents in China showed an overall decline.Children under 10 years old are high risk population.关键词
哮喘/年龄-时期-队列模型/Joinpoint回归模型/中国/儿童青少年Key words
asthma/age-period-cohort model/Joinpoint regression model/China/children and adolescents分类
医药卫生引用本文复制引用
陈海英,樊慧,杨洋,杜文哲,郝长付..1990-2019年中国儿童青少年哮喘发病率与死亡率变化趋势分析[J].郑州大学学报（医学版）,2025,60(2):216-220,5.基金项目
国家自然科学基金面上项目(82173491) （82173491）
