岭南现代临床外科2025，Vol.25Issue(1)：36-40,5.DOI:10.3969/j.issn.1009-976X.2025.01.007
52例肺浸润性腺癌的临床病理特征及肺门纵隔淋巴结转移风险因素分析
Clinical and pathological characteristics of 52 cases of pulmonary invasive adenocarcinoma and analysis of risk factors for hilar and mediastinal lymph node metastasis
王道笃 1赵其炯 1周志标 1陈鑫1
作者信息
- 1. 汕尾逸挥基金医院肿瘤外科,广东 汕尾 516600
- 折叠
摘要
Abstract
Objective This study aims to retrospectively analyze the clinicopathological characteristics and risk factors for hilar and mediastinal lymph node metastasis in non-small cell lung adenocarcinoma.Methods We conducted a retrospective analysis of 52 patients with invasive adenocarcinoma who underwent initial surgery and had postoperative pathology reports from October 2018 to October 2023 at the Oncological Surgery Department of Shanwei Second People's Hospital.We investigated the risk factors for hilar mediastinal lymph node metastasis,and used chi-square tests and logistic regression models to find the threshold points of risk factors through the ROC curve.Results Regarding clinicopathological characteristics,the male-to-female ratio was 0.92∶1,with 6 patients(11.5%)developing lymph node metastasis.Univariate analysis revealed that a primary tumor diameter≥2 cm and CEA≥5 ng/mL increased the risk of hilar and mediastinal lymph node metastasis(P<0.05).Multivariate logistic analysis demon-strated that a tumor maximum diameter of≥2 cm was a statistically significant risk factor for lymph node metastasis(P<0.05).Conclusion In patients with invasine adenocarcinoma of the lung,a tumor mass larger than 2 cm and aserum CEA level of 5 ng/mL are risk factors for lymph node metastasis.关键词
非小细胞肺癌/肿瘤最大直径/癌胚抗原/淋巴结转移Key words
non-small cell lung cancer/maximum tumor diameter/lymph node metastasis分类
医药卫生引用本文复制引用
王道笃,赵其炯,周志标,陈鑫..52例肺浸润性腺癌的临床病理特征及肺门纵隔淋巴结转移风险因素分析[J].岭南现代临床外科,2025,25(1):36-40,5.
