检验医学与临床2025，Vol.22Issue(7)：940-945,6.DOI:10.3969/j.issn.1672-9455.2025.07.016
新疆生产建设兵团全血细胞计数检测结果一致性调查
Agreement investigation of complete blood cell count test results in Xinjiang production and construction corps
摘要
Abstract
Objective To evaluate the agreement of complete blood count(CBC)test results across clinical laboratories within the leading units of the Xinjiang Production and Construction Corps(referred to as"XPCC")medical consortium.Methods Five CBC items including white blood cell count(WBC),red blood cell count(RBC),hemoglobin(Hb),platelet count(PLT),hematocrit(HCT)and within-day precision of in-ternal quality control(CV)data of clinical laboratories of 19 medical alliances or medical alliances leading u-nits in March and September 2023 were extracted.The measurement results for these 5 projects were collected from 3 batches of survey samples across the 19 clinical laboratories,followed by a statistical analysis of the da-ta.Results The internal quality control CVs for all 12 laboratories over a two-month period for CBC and 5 projects met the industry standard requirements.However,only one project,the WBC,fulfilled the industry standard requirements from all laboratories'internal quality control CVs for the two-month period.The mean(x)and the range(R)of the test results for 3 batches and 5 projects from 19 laboratories were as follows WBC 3.08×109/L,0.70×109/L,13.28×109/L,2.64×109/L and 4.66×109/L,0.71×109/L;RBC 2.74×1012/L,0.13×1012/L,5.72×1012/L,0.40×1012/L and 3.94×1012/L,0.20×1012/L;Hb 53.32 g/L,4.00 g/L,108.95 g/L,10.00 g/L and 71.74 g/L,5.00 g/L;PLT 99.37×109/L,54.00×109/L,240.63×109/L,60.00×109/L,and 204.63×109/L,92.00×109/L;HCT 17.86%,3.30%,39.52%,7.90%and 24.86%,4.90%.The agreement of RBC and Hb measurement results from 19 laboratories was satisfactory,whereas the agreement of other parameters was somewhat less favorable.A comparison of detection results from 3 bat-ches and 5 projects between the Mindray detection system(14 laboratories)and the Sysmex detection system(5 laboratories)indicated that there were statistically significant differences in the test results of WBC batch 2,Hb batches 1 and 2,PLT batches 1 and 3,and HCT batches 1,2 and 3 between the two detection systems(all P<0.05).The relative deviations of PLT batches 1 and 3 between the two detection systems were over 20%,and those of HCT batches 1 and 3 were over 10%.Conclusion The clinical laboratory CBC test results from the leading units of the XPCC Medical Consortium or Medical Community generally demonstrate good a-greement.However,it is essential to strengthen the management of CBC internal quality control and to pay at-tention to the differences in test results among various testing systems.This approach will facilitate the mutu-al recognition of laboratory results.关键词
全血细胞计数/检测系统/日间精密度/一致性/结果互认Key words
complete blood cell count/detection system/within-day precision/agreement/mutual recognition of laboratory result分类
医药卫生引用本文复制引用
宋颖博,梁梦洁,邓朝晖,张新..新疆生产建设兵团全血细胞计数检测结果一致性调查[J].检验医学与临床,2025,22(7):940-945,6.基金项目
国家临床重点专科建设项目[兵财社(2023)16号] （2023）
兵团检验医学临床医学研究中心建设项目[兵科发(2023)12号]. （2023）
