摘要
Abstract
With the widespread use of antibiotics in healthcare,agriculture and animal husbandry,a serious problem of bacterial resistance has emerged globally,posing significant risks to disease treatment,human health and the ecological environment.How to address antibiotic resistance is an important challenge faced globally.This article summarizes the high abundance and high detection rate of antibiotic resistance gene fami-lies and their subtypes,explores the distribution characteristics of antibiotic resistance genes in different habi-tats,analyzes the migration and transmission mechanisms of antibiotic resistance genes,and elucidates the manifestations and health risks of antibiotic resistance in clinical practice.At present,there are many problems in the research of antibiotic resistance,such as the abuse of antibiotics in clinical practice,rapid spread and cross infection of drug-resistant strains,lack of data sharing and international cooperation,and unclear re-search on diverse resistance mechanisms.This review aims to provide new ideas for the study of clinical dis-ease treatment,rapid spread and cross infection of drug-resistant strains,diverse resistance mechanisms and human animal environmental health risks by summarizing the introduction.It is exprected to slow down effec-tively the development of drug resistance through various comprehensive means such as the development of al-ternative medicine,interdisciplinary cooperation and technological innovation,rational use and management,exploration and development of new antibiotics,international cooperation and policy formulation.关键词
抗菌药物/耐药基因/分布/传播/生物环境/健康风险Key words
antibiotic/resistance gene/distribution/transmission/biological environment/health risk分类
医药卫生
