宁夏大学学报（自然科学版）2025，Vol.46Issue(1)：59-67,9.
微生物转录因子工程的研究进展
Research Advances in Microbial Transcription Factor Engineering
摘要
Abstract
With the rapid development of synthetic biology,microbial cell factories have emerged as a pivotal platform for green biomanufacturing.Transcription factor engineering,a technology that utilizes transcription factors to regulate gene expression,enables simultaneous modulation of multiple genes within metabolic path-ways.This approach plays a crucial role in microbial metabolic engineering and synthetic biology research.This review introduces the fundamental concepts and regulatory mechanisms of transcription factors,summarizes recent advances in microbial transcription factor studies and their engineering applications,and discusses current challenges and future directions in this field.关键词
转录因子/转录因子工程/调控机制/耐受性/生物传感器Key words
transcription factors/transcription factor engineering/regulatory mechanism/tolerance/biosensors分类
生物学引用本文复制引用
梁志慧,陆孔泳,郑洋洋,王智文..微生物转录因子工程的研究进展[J].宁夏大学学报（自然科学版）,2025,46(1):59-67,9.基金项目
国家自然科学基金资助项目(NSFC-22278312) （NSFC-22278312）
宁夏回族自治区中央引导地方科技发展专项基金资助项目(2024FRD05057) （2024FRD05057）
宁夏重点研发基金资助项目(2024BEE02005) （2024BEE02005）
