宁夏大学学报（自然科学版）2025，Vol.46Issue(1)：68-77,10.
细胞外囊泡在细菌和病毒感染中的免疫调控作用
Immune Regulatory Roles of Extracellular Vesicles in Bacterial and Viral Infections
摘要
Abstract
Extracellular vesicles(EVs),membrane-enclosed heterogeneous particles secreted by cells,have gar-nered significant attention for their ability to transport bioactive molecules(e.g.,proteins and RNA)to recipi-ent cells,thereby modulating immune responses or pathogenic processes.While the biogenesis of EVs under physiological and pathological conditions has been extensively characterized,the mechanisms by which patho-gen infections influence EVs release and how host-derived EVs regulate immune responses during infections remain poorly understood.EVs secreted by infected cells contain both host-and pathogen-derived molecules,which may either promote pathogen virulence or enhance host anti-infective immunity.This review systemati-cally summarizes recent advances in understanding the dual roles of EVs in immune regulation and pathogenesis during bacterial and viral infections.关键词
细胞外囊泡/生物发生/免疫反应/细菌感染/病毒感染Key words
extracellular vesicles/biogenesis/immune regulation/bacterial infection/viral infection分类
临床医学引用本文复制引用
吴一鸣,赵刚,王玉炯..细胞外囊泡在细菌和病毒感染中的免疫调控作用[J].宁夏大学学报（自然科学版）,2025,46(1):68-77,10.基金项目
国家自然科学基金资助项目(U22A20505,32473030) （U22A20505,32473030）
