山东医药2025，Vol.65Issue(3)：144-149,6.DOI:10.3969/j.issn.1002-266X.2025.03.030
膝关节骨髓水肿的病因学分类及诊治进展
Etiological classification and progress in diagnosis and treatment of bone marrow edema in knee joint
摘要
Abstract
Knee bone marrow edema(BME)is a common knee joint pathology characterized by its self-limiting na-ture.However,if left untreated,it can lead to progressive wear of articular cartilage and potentially evolve into end-stage osteoarthritis,significantly impairing the patients'quality of life.The etiology of knee BME is complex and can generally be categorized into ischemic,mechanical,and reactive types.Ischemic knee BME is often associated with microcirculato-ry disturbances,including conditions such as osteonecrosis,bone marrow edema syndrome,osteochondritis dissecans,and complex regional pain syndrome.Mechanical knee BME is typically caused by trauma or stress-related injuries,en-compassing bone contusions,stress-related BME,and stress fractures.Reactive knee BME is closely linked to inflammato-ry responses in surrounding tissues,including inflammatory arthritis of the knee,knee osteoarthritis,postoperative BME,and tumor-associated BME.The primary treatment for knee BME is conservative management,which includes pharmaco-logical interventions and physical therapy.If conservative measures fail,minimally invasive protective surgery may be con-sidered.In cases where there is extensive cartilage degeneration and subchondral bone collapse,total knee arthroplasty or unicompartmental knee arthroplasty remains the only effective treatment option.关键词
骨髓水肿/骨关节炎/膝关节疾病/全膝关节置换术/单髁膝关节置换术Key words
bone marrow edema/osteoarthritis/knee joint disorders/total knee arthroplasty/unicompartmental knee arthroplasty分类
医药卫生引用本文复制引用
师锦玉,刘沛,李建垒,石腾博,杨鹏,曹向阳..膝关节骨髓水肿的病因学分类及诊治进展[J].山东医药,2025,65(3):144-149,6.基金项目
河南省重大科技专项(221100310200) （221100310200）
河南省工程研究中心建设项目[豫发改高技(2018)1030号] （2018）
河南省医学科技攻关联合共建项目(LHGJ20230482). （LHGJ20230482）
