摘要
Abstract
Objective:To analyze the clinical value of serum cystatin(CysC)and coagulation function in patients with acute cerebral infarction.Methods:Data 30 patients with acute cerebral infarction admitted to Jinqiu Hospital of Liaoning Province from February 2021 to June 2023 were retrospectively analyzed and enrolled into the study group;another 30 healthy patients who underwent physical examination in the same period were selected and included in the control group.CysC and coagulation function test were performed in both groups.The test results of the two groups were compared,and the study group was divided into complete cerebral infarction group and progressive cerebral infarction group according to disease type.The CysC and coagulation function test results of acute cerebral infarction patients in the two groups were compared.The clinical value of CysC and coagulation function in patients with acute cerebral infarction and different types of acute cerebral infarction was analyzed by receiver operating characteristic(ROC)curve.Results:The levels of CysC and fibrinogen(FIB)in the study group were higher than those in the control group,and the prothrombin time(PT),activated partial thrombin time(APTT)and thrombin time(TT)in the study group were shorter than those in the control group,with statistical significance(P<0.05).ROC curve analysis showed that the area under the crure(AUC)of CysC combined with coagulation function test in the diagnosis of acute cerebral infarction was 0.904,which was higher than those of each index alone.The levels of CysC and FIB in progressive cerebral infarction group were lower than those in complete cerebral infarction group,and PT,APTT and TT were longer than those in complete cerebral infarction group,the differences were statistically significant(P<0.05).ROC curve analysis showed that the AUC of CysC and coagulation function combined detection in the diagnosis of different types of acute cerebral infarction patients was 0.996,which was higher than those of each index alone.Conclusion:CysC and coagulation function test in patients with acute cerebral infarction can clarify the condition of patients,evaluate the disease type of patients,and provide reference for clinical treatment,which has certain clinical application value.关键词
急性脑梗死/血清胱抑素C/凝血功能/检验价值Key words
Acute cerebral infarction/Serum cystatin C/Coagulation function/Inspection value分类
临床医学
