兰州大学学报（医学版）2025，Vol.51Issue(2)：1-9,9.DOI:10.13885/j.issn.1000-2812.2025.02.001
循证医学驱动临床前动物实验成果的转化与利用
Evidence-based medicine driving the translation and application of preclinical animal experiment results
摘要
Abstract
Preclinical animal experiments,as a bridge for translating basic medical research into clinical appli-cations,had long faced challenges such as poor reproducibility and low translation rates.Evidence-based medicine,through the continuous accumulation of evidence and its scientific validation and application has provided new perspectives,tools,methods,approaches,and evidence to address these challenges in preclinical animal experiments.Based on the limitations and challenges that existed in the translational application of pre-clinical animal experiments,as well as the opportunities for development,this study systematically analyzed how the theoretical framework of evidence-based medicine had been applied to enhance the scientific rigor and reliability of preclinical animal experiment outcomes.Furthermore,it explored the opportunities and chal-lenges that had arisen in the translation of preclinical animal experiment findings,considering the trends in the development of evidence-based medicine.关键词
循证医学/动物实验/基础医学/成果转化/实验动物/临床前研究Key words
evidence-based medicine/animal experiment/basic medicine/result translation/laboratory animal/preclinical study分类
基础医学引用本文复制引用
易少威,张俊华,马彬..循证医学驱动临床前动物实验成果的转化与利用[J].兰州大学学报（医学版）,2025,51(2):1-9,9.基金项目
甘肃省自然科学基金资助项目(5JRRA046) （5JRRA046）
兰州市科技计划资助项目(2022-3-8) （2022-3-8）
