陕西中医2025，Vol.46Issue(4)：486-489,4.DOI:10.3969/j.issn.1000-7369.2025.04.011
固本抗癌方治疗乳腺癌术后化疗患者骨髓抑制临床疗效
Clinical effect of Guben Kang'ai prescription on myelosuppression in patients with breast cancer after chemotherapy
摘要
Abstract
Objective:To observe the effect of Guben Kang'ai prescription on myelosuppression of postoperative chemotherapy for breast cancer.Methods:A total of 80 cases of postoperative chemotherapy for breast cancer were selected as research subjects,all the enrolled pathologies were randomly divided into 40 cases each in the control and observation groups according to the random number table method,the control group was treated routinely,and the observation group was orally administered with Guben Kang'ai prescription,and the bone marrow suppression of the two groups was observed.Results:After 4 and 8 weeks of treatment,TCM syndrome scores in the observation group were significantly lower than those in the control group(all P<0.05).The levels of leukocyte,platelet and hemoglo-bin in observation group were significantly higher than those in control group(all P<0.05).After treatment,the in-cidence of myelosuppression above Ⅲ degree in observation group was significantly lower than that in control group(all P<0.05).The dosage of granulocyte colony-stimulating factor(GCS-F)and the time required for normal blood routine in observation group were significantly lower than those in control group(all P<0.05).After treatment,the quality of life score(QOL)and KPS score in the observation group were significantly higher than those in the control group(all P<0.05).Conclusion:In the treatment of patients with breast cancer after chemotherapy,Guben Kang'ai prescription can significantly reduce clinical symptoms,improve the quality of life of patients,improve blood cell ab-normalities,reduce bone marrow suppression,reduce the amount of GCS-F,and promote the normal blood routine.关键词
乳腺癌/固本抗癌方/辅助化疗/骨髓抑制/免疫功能/生活质量Key words
Breast cancer/Guben Kang'ai prescription/Adjuvant chemotherapy/Myelosuppression/Immune function/Quality of life分类
医药卫生引用本文复制引用
董文敏,秦旭辉,任伊宁,冯浩,徐曌,兴伟..固本抗癌方治疗乳腺癌术后化疗患者骨髓抑制临床疗效[J].陕西中医,2025,46(4):486-489,4.基金项目
河北省中医药管理局科研计划项目(2025019) （2025019）
