陕西中医2025，Vol.46Issue(4)：512-516,5.DOI:10.3969/j.issn.1000-7369.2025.04.017
基于"亢火害物"探讨结直肠"炎-癌转化"及防治思路
The prevention and treatment of colorectal"inflammation cancer transformation"based on"raging inferno and injuring wu"
摘要
Abstract
Colorectal cancer is a common malignant tumor of the gastrointestinal tract.Inflammation is consid-ered to be one of the main causes of colorectal cancer,and the inflammatory microenvironment it generates signifi-cantly increases the risk of colorectal cancer.Therefore,improving the inflammatory microenvironment of tumors and slowing down the process of"inflammation-cancer transformation"are of great significance to the prevention and treatment of colorectal cancer.According to Chinese medicine,fire-heat toxicity is closely related to inflammation in modern medicine.Based on the analogy by appearance of Chinese medicine and modern medical research,the author believes that"raging inferno and injuring wu"can be used to describe the development process of"inflammation cancer transformation"."Raging inferno"is the basis for the development of"inflammation cancer transformation"throughout the whole process,and"injuring wu"is the root cause of its formation.Hyperactive fire accumulation on the one hand can be transformed into poison fumigation bowel derived from it,on the other hand,the harm loss of positive qi,so that the human body is in a state of deficiency and can not get rid of the evil in the outside,which makes the fire become toxic to the deficiency,and the fire and toxicity due to the deficiency into a vicious circle,accel-erates the process of"inflammation cancer transformation".Therefore,for the treatment of"Kang hai cheng zhi"should take care of both positive and negative aspects,replenish the deficiency of human body's qi and blood,clear and reduce the reality of fire and toxicity,reduce the inflammatory infiltration,prevent the formation of"inflamma-tion-dysplasia-cancer"transformation sequence,so as to effectively reduce the development of colorectal cancer.关键词
结直肠癌/亢火害物/亢害承制/炎-癌转化/炎症/微环境Key words
Colorectal cancer/Raging inferno and injuring wu/Kang hai cheng zhi/Inflammation cancer trans-formation/Inflammation/Microenvironment分类
医药卫生引用本文复制引用
宁永波,罗珍莲,宋子豪,王雅兴,陈香颖,陈嘉齐,吴存恩,薛维伟,壮雨雯..基于"亢火害物"探讨结直肠"炎-癌转化"及防治思路[J].陕西中医,2025,46(4):512-516,5.基金项目
国家自然科学基金资助项目(82205210) （82205210）
江苏省中医院院级课题(Y2020CX67) （Y2020CX67）
