陕西中医2025，Vol.46Issue(4)：555-558,563,5.DOI:10.3969/j.issn.1000-7369.2025.04.026
火针焠灸联合针刺治疗卒中后失眠临床研究
Clinical study on fire needle tempering and moxibustion combined with acupuncture in the treatment of post-stroke insomnia
摘要
Abstract
Objective:To observe the clinical efficacy of fire needle moxibustion combined with acupuncture in the treatment of post-stroke insomnia(PSI).Methods:70 patients with PSI were randomized into observation and control groups of 35 patients.On the basis of western basic treatment and conventional rehabilitation training,the control group was treated with conventional acupuncture.The observation group was treated with fire needle moxi-bustion based on the treatment of the control group.Both groups were treated once every other day,three times a week for 4 weeks.Pittsburgh Sleep Quality Index,National Institutes of Health Stroke Scale,Insomnia Severity Index Index,and Fatigue Assessment Scale(FAS)scores were assessed before and after treatment.Levels of IL-1β,IL-2,PCT,Glu and GABA and glutamate Glu/GABA ratio were measured before and after treatment,and efficacy and safety were assessed.Results:PSQI,NIHSS,ISI and FAS scores decreased in both groups(all P<0.05),IL-1β,IL-2,PCT,Glu levels and Glu/GABA ratio all decreased(all P<0.05),GABA level increased(all P<0.05),and decrea-ses/increases were more pronounced in the observation observation group(all P<0.05).The overall efficacy in the observation group was 91.43%,significantly higher than in the control group(77.14%)(P<0.05).During the treatment period,no adverse reactions occurred in both groups.Conclusion:Fire needle tempering and moxibustion combined with acupuncture can effectively improve the sleep quality,the degree of impaired neurological function,and the degree of fatigue in PSI patients,and its mechanism of action may be related to the regulation of serum inflamma-tory factors,neurotransmitter levels,and the balance of neural excitability/inhibitability.关键词
卒中/失眠/针刺/炎症因子/神经递质/白细胞介素Key words
Stroke/Insomnia/Acupuncture/Inflammatory factor/Neurotransmitter/Interleukin分类
医药卫生引用本文复制引用
陈希阳,朱才丰,杨高尚,谢苗苗,袁心怡,叶淑琦,张振丰..火针焠灸联合针刺治疗卒中后失眠临床研究[J].陕西中医,2025,46(4):555-558,563,5.基金项目
国家优势专科老年病科建设项目[国中医药医政函(2024)90号] （2024）
安徽省自然科学基金资助项目(2208085MH273) （2208085MH273）
安徽省中医药传承创新科研项目(2024CCCX004) （2024CCCX004）
安徽省华佗中医药研究院科技重大专项"揭榜挂帅"项目(BZKZ2402) （BZKZ2402）
