畜牧与兽医2025，Vol.57Issue(4)：14-19,6.
丹系大白猪与亚洲野猪全基因组选择信号分析
Analysis of genome-wide selection signatures in Danish Large White pig and Asian Sus scrofa
摘要
Abstract
The aim of this study was to analyze the differences in genomic selection sweeps between Danish Large White(LW)and Asian Sus scrofa(SS)pigs.We obtained genetic variation information from 43 LW and 6 SS pigs using the whole-genome resequencing technology.Selection regions were detected using both Fst and π ratio methods,and functional enrichment analysis was performed on the genes within these regions.The results showed that there were 134 selection regions in the LW pigs compared with the SS ones;these regions contained 103 genes.The GO functional enrichment terms were mainly involved in enzyme metabolism,while the KEGG functional pathways were asso-ciated with growth and reproduction.After screening,five candidate genes related to the reproductive performance of the Landrace pigs,namely APC2,AQP9,KISS1R,PAPPA2,and PTBP1,were found to be under strong positive selection.The results of this study further elucidated the genetic basis of the high reproductive performance of LW pigs and provided references for the domestication and selection of foreign breeds and the development of molecular markers for related economic traits.关键词
丹系大白猪/亚洲野猪/全基因组重测序/选择清除/候选基因Key words
Danish Large White pig/Asian Sus scrofa/whole genome resequencing/selective sweep/candidate gene分类
农业科技引用本文复制引用
吴旭东,刘孟全,李默,张威,吴涛,赵子龙,殷宗俊..丹系大白猪与亚洲野猪全基因组选择信号分析[J].畜牧与兽医,2025,57(4):14-19,6.基金项目
安徽省科技重大专项项目(202203a06020031) （202203a06020031）
安徽省瘦肉型种猪选育与种质创新联合攻关项目 （）
