中国防痨杂志2025，Vol.47Issue(4)：482-497,16.DOI:10.19982/j.issn.1000-6621.20240567
基于文献计量学的结核病中医药基础研究全球研究现状及热点分析
Bibliometric analysis of global research status and hotspots in the basic research of Traditional Chinese Medicine for tuberculosis
摘要
Abstract
Objective:To explore the global research status and trends in basic research on Traditional Chinese Medicine(TCM)for prevention and treatment of tuberculosis(TB).Methods:We conducted a comprehensive literature review of Chinese and English publications related to basic TCM research against TB using Chinese national knowledge infrastructure,Wanfang database,PubMed and Web of Science database with a cutoff date of June 30,2024.Bibliometric analysis was performed using CiteSpace and VOSviewer software to visualize publication metrics,author and institution networks,keywords clusters and the frequency of TCM interventions in both Chinese and English literature.Results:A total of 140 articles were included,contributed by 546 authors from 190 institutions,including 102 Chinese articles(72.86％)and 38 English articles(27.14％).The first publication appeared in 1961,with a noticeable increase in research output observed since 1993.In terms of journal distribution,the journal with the most Chinese publications was Chinese Journal of Antituberculosis(6.86％,7/102),and the journal with the most English publications was Journal of Ethnopharmacology(10.53％,4/38).Regarding author collaboration networks,the Chinese literature formed two research terms centered around"Wang Lixin and Wang Yi","Pan Jianhua,Shi Guomin,Xiang Yangen,Yu Rong",respectively,while the English literature formed research teams centered around"Jiang Xin,Sun Jinxia,Zheng Yuejuan".The institution collaboration network centered around"Shanghai University of Traditional Chinese Medicine"and"Changzhi Medical College."Keyword clustering analysis in both Chinese and English literature revealed 16 distinct clusters,with research hotspots primarily concentrating on antibacterial effects and immunomodulation.Additionally,Prunella vulgaris,Radix Ranunculi Ternati,Radix stemonae,Rhubarb,Garlic were the most concerned single herb;baicalin,Radix Ranuncoli Ternati extracts,Allicin and Curcumin were the most TCM ingredients or extracts;while the combination of Bletilla striata(Thunb.ex A.Murray)Rchb.f.and Stemona japonica(Blume)Miq.(Bai Ji-Bai Bu)as the most strongly correlated herbal pair in TCM formulations.Conclusion:Basic research on TCM against TB has gained significant traction globally in recent years.The antibacterial effects and immune regulation mechanisms of TCM may become the future focus of development.Future investigations should enhance cross-sector and interdisciplinary collaborations to further elucidate the mechanisms underpinnings and optimize therapeutic patterns of TCM in TB prevention and treatment.关键词
结核/医学,中国传统/基础研究/文献计量学Key words
Tuberculosis/Medicine,Chinese Traditional/Basic research/Bibliometrics分类
临床医学引用本文复制引用
尚希钰,张慧芳,曹玉清,熊一白,纪鑫毓,田雅欣,李佳佳,王倪,马艳..基于文献计量学的结核病中医药基础研究全球研究现状及热点分析[J].中国防痨杂志,2025,47(4):482-497,16.基金项目
国家重点研发计划(2023YFC3503400) （2023YFC3503400）
国家自然科学基金(82274350) National Key Research and Development Program of China(2023YFC3503400) （82274350）
National Natural Science Foundation of China(82274350) （82274350）
