中国防痨杂志2025，Vol.47Issue(4)：498-504,7.DOI:10.19982/j.issn.1000-6621.20240527
结核后肺曲霉病的临床诊疗研究进展
Advances in the clinical diagnosis and treatment of post-tuberculosis chronic pulmonary aspergillosis
摘要
Abstract
Tuberculosis(TB)remains the leading cause of death from infectious diseases globally.Increasing recognition has been given to the long-term consequences of post-tuberculosis lung disease(PTLD),which profoundly affect patients'physical health,psychological well-being,and socioeconomic stability.Among these sequelae,post-tuberculosis chronic pulmonary aspergillosis(PTLD-CPA)is a persistent Aspergillus infection that arises during or after TB treatment.The substantial overlap in clinical manifestations and radiological features between CPA and TB frequently leads to misdiagnosis and inappropriate treatment,further exacerbating disease progression and associated morbidity.This underscores the critical need for early screening and timely intervention for Aspergillus infection.This review consolidates current evidence on the epidemiology,clinical characteristics,diagnostic modalities,treatment strategies,and screening protocols for PTLD-CPA.By delineating key priorities for prevention and disease management,we propose a comprehensive,life-cycle-based health management framework for TB,integrating early detection,targeted therapeutic interventions,and long-term surveillance to mitigate the enduring burden of PTLD-CPA.关键词
结核,肺/曲霉菌病/结核后肺疾病/综述Key words
Tuberculosis,pulmonary/Aspergillosis/Post-tuberculosis lung disease/Review分类
临床医学引用本文复制引用
秦丽莉,杨澄清,麦洪珍,徐齐峰,薛新颖,路希维..结核后肺曲霉病的临床诊疗研究进展[J].中国防痨杂志,2025,47(4):498-504,7.基金项目
The Project of Dalian Medical Key Specialty"Top Specialty Program"(21020021T0000 00006625)大连市"登峰计划"医学重点专科建设项目经费资助(21020021T0000 00006625) （21020021T0000 00006625）
