中国防痨杂志2025，Vol.47Issue(4)：520-526,7.DOI:10.19982/j.issn.1000-6621.20240547
肺结核与肠道菌群的相关性及治疗策略
Association between pulmonary tuberculosis and the gut microbiota:treatment strategies
摘要
Abstract
Tuberculosis(TB)remains a prevalent respiratory infectious disease worldwide.In recent years,accumulating evidence has highlighted a strong association between the gut microbiota and TB pathogenesis.The gut microbiota plays a critical role in modulating TB immunity through the gut-lung axis,while TB infection itself can induce significant dysbiosis in the intestinal microbial ecosystem.This review explores the bidirectional interplay between Mycobacterium tuberculosis(MTB)infection and the gut microbiota,elucidates the immunological mechanisms underlying their interaction,and discusses the therapeutic potential of microbiome-based interventions for TB.These insights may contribute to the development of novel treatment strategies for TB management.关键词
结核,肺/肠杆菌科/免疫系统Key words
Tuberculosis,pulmonary/Enterobacteriaceae/Immune system分类
临床医学引用本文复制引用
李敏,姚宇珊,乔海霞,雷红..肺结核与肠道菌群的相关性及治疗策略[J].中国防痨杂志,2025,47(4):520-526,7.基金项目
Institutional Research Project of the Eighth Medical Center,General Hospital of the Chinese People's Liberation Army(MS202211004) 解放军总医院第八医学中心院级研究课题计划(MS202211004) （MS202211004）
