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非感染性葡萄膜炎继发脉络膜新生血管的多模式影像特征

杨诗诗 文峰 张雄泽 陈雪琳 甘雨虹

眼科学报2025,Vol.40Issue(3):241-251,11.
眼科学报2025,Vol.40Issue(3):241-251,11.DOI:10.12419/24110106

非感染性葡萄膜炎继发脉络膜新生血管的多模式影像特征

Multimodal imaging features of choroidal neovascularization secondary to non-infectious uveitis

杨诗诗 1文峰 1张雄泽 1陈雪琳 1甘雨虹1

作者信息

  • 1. 中山大学中山眼科中心,眼病防治全国重点实验室,广东省眼科视觉科学重点实验室,广州 510060
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摘要

Abstract

Objective:To evaluate the clinical characteristics and multimodal imaging features of non-infectious inflammatory choroidal neovascularization(iCNV).Methods:In this study retrospective,observational study,multimodal imaging examinations,including fluorescein angiography(FFA),indocyanine green angiography(ICGA),spectral-domain optical coherence tomography(SD-OCT),and optical coherence tomography angiography(OCTA),were used to observe the morphology of non-infectious iCNV in patients diagnosed with uveitis.The area of iCNV,CNV types,CNV morphology and other imaging characteristics were further analyzed.Results:A total of 39 patients were included,with 48 affected eyes and 51 iCNV were identified.The average age of the included patients was 35.28±13.62 years.Among the affected eyes,3 presented with multifocal CNV,and 92.16%of iCNV were classified as type 2 CNV.iCNV exhibited diverse morphologies,including focal-like pattern(15 cases,29.41%),sea-fan pattern(16 cases,31.37%),dead-tree pattern CNV(9 cases,17.65%),stellar pattern(9 cases,17.65%),and diffuse reticular(2 cases,3.92%).Notably,tree-like and stellar pattern iCNV showed a significant correlation with non-active CNV(P<0.01).Conclusions:Non-infectious iCNV is closely related to inflammatory lesions,exhibiting characteristic imaging features on SD-OCT and ICGA.OCTA allows for direct observation of the morphology of iCNV.These multimodal imaging characteristics provide important diagnostic criteria for clinicians,aiding in the formulation of effective treatment plans.

关键词

脉络膜新生血管/眼底多模式影像/光学相干断层扫描血管成像

Key words

choroidal neovascularization/multimodal imaging/optical coherence tomography angiography

分类

临床医学

引用本文复制引用

杨诗诗,文峰,张雄泽,陈雪琳,甘雨虹..非感染性葡萄膜炎继发脉络膜新生血管的多模式影像特征[J].眼科学报,2025,40(3):241-251,11.

眼科学报

1000-4432

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