中国免疫学杂志2025，Vol.41Issue(3)：756-759,4.DOI:10.3969/j.issn.1000-484X.2025.03.043
抗菌肽LL-37与自身免疫性疾病的研究进展
Research progress of antimicrobial peptide LL-37 and autoimmune diseases
摘要
Abstract
LL-37 is a widely-distributed human antimicrobial peptide with antimicrobial activity.In recent years,it has been found that LL-37 not only has antibacterial effect,but also can exert comprehensive immune regulatory function on different immune cells in different microenvironments,and then play a pro-inflammatory or anti-inflammatory role in a series of autoimmune diseases.This article focuses on immunomodulatory effect of LL-37 and its possible role in autoimmune diseases.关键词
LL-37/抗菌肽/自身免疫性疾病/免疫调节Key words
LL-37/Antimicrobial peptide/Autoimmune disease/Immunoregulation分类
医药卫生引用本文复制引用
吴梦静,张大启,李其富,廖小平..抗菌肽LL-37与自身免疫性疾病的研究进展[J].中国免疫学杂志,2025,41(3):756-759,4.基金项目
国家自然科学基金(81760244) （81760244）
海南省自然科学基金面上项目(820MS140). （820MS140）
