中国全科医学2025，Vol.28Issue(17)：2082-2091,2112,11.DOI:10.12114/j.issn.1007-9572.2024.0696
内分泌代谢系统疾病与继发性骨质疏松症的研究新进展
Progress in the Research of Endocrine and Metabolic System Diseases and Secondary Osteoporosis
摘要
Abstract
Secondary osteoporosis(OP)is mostly related to endocrine and metabolic diseases.The growth and development of bone is inseparable from the regulation of the endocrine system.Endocrine and metabolic diseases such as hyperthyroidism,hypogonadism,and hyperprolactinemia can break the balance between bone resorption and bone formation,and increase the risk of osteoporosis and fracture.In order to effectively manage secondary OP caused by endocrine and metabolic diseases,it is particularly important to explore its mechanism,diagnostic methods and treatment options.This article reviews the epidemiological characteristics of secondary osteoporosis in different groups of endocrine and metabolic diseases,the pathogenesis of hormone imbalance and cell signaling pathway abnormalities,the characteristics of bone damage such as bone metabolism indicators and bone mineral density,and the progress in the diagnosis and treatment of secondary osteoporosis,so as to provide reference for the prevention and treatment of secondary osteoporosis in patients with endocrine and metabolic diseases.关键词
继发性骨质疏松症/骨质疏松/甲状腺功能亢进症/高泌乳素血症/性腺功能减退症/发病机制/治疗Key words
Secondary osteoporosis/Osteoporosis/Hyperthyroidism/Hyperprolactinemia/Hypogonadism/Pathogenesis/Treatment分类
临床医学引用本文复制引用
陈钡钡,李佳,谭文彬..内分泌代谢系统疾病与继发性骨质疏松症的研究新进展[J].中国全科医学,2025,28(17):2082-2091,2112,11.基金项目
国家重点研发计划(2021YFC2501701) （2021YFC2501701）
广东省中央引导地方科技发展专项基金(KTP20190249) （KTP20190249）
