中国医药科学2025，Vol.15Issue(5)：159-162,4.DOI:10.20116/j.issn2095-0616.2025.05.37
阿芬太尼联合苯磺酸瑞马唑仑在宫腔镜手术中的应用研究
Application research of fentanyl combined with remimazolam besylate in hysteroscopy surgery
摘要
Abstract
Objective To investigate the efficacy of the combination of fentanyl and remazolam besylate in hysteroscopy surgery.Methods Patients who underwent hysteroscopy surgery at Liuzhou Workers'Hospital of the Fourth Affiliated Hospital of Guangxi Medical University from January 2021 to December 2023 were selected and divided into the observation group(n=50,anesthetized with fentanyl and remazolam besylate).By propensity pairing,patients who underwent the same surgery simultaneously were selected and divided into the control group(n=50,anesthetized with fentanyl and propofol).The data of two groups of patients were retrospectively evaluated.The average arterial blood pressure,heart rate,respiratory rate,and blood oxygen saturation between two groups at 3 time points before anesthesia,disappearance of eyelash reflex,and cervical dilation were compared.The pain levels and Ramsay sedation scores of two groups at 6,12,and 24 hours after surgery were evaluated.Two related perioperative indices(anesthesia onset time,operative duration,and respiratory recovery time)were compared.Results There were no statistically significant differences in the average arterial blood pressure,heart rate,respiratory rate,and blood oxygen saturation between the two groups of patients at 3-time points before anesthesia,disappearance of eyelash reflex,and cervical dilation(P>0.05).The visual analogue scale of the observation group was significantly lower than that of the control group at 6,12,and 24 hours after surgery,with statistically significant difference(P<0.05).There was no statistically significant difference in Ramsay sedation score between the two groups of patients at different postoperative time points(P>0.05).There was no statistically significant difference in the operative duration between the two groups(P>0.05).The onset time of anesthesia and respiratory recovery time in the observation group were significantly shorter than those in the control group,with statistically significant differences(P<0.05).Conclusion The combination therapy of fentanyl and remimazolam besylate in hysteroscopy surgery has shown more satisfactory results and is recommended to be promoted in practice.关键词
阿芬太尼/苯磺酸瑞马唑仑/宫腔镜/丙泊酚/麻醉诱导Key words
Fentanyl/Remimazolam besylate/Hysteroscopy/Propofol/Anesthesia induction分类
临床医学引用本文复制引用
蔡广雄,唐斌..阿芬太尼联合苯磺酸瑞马唑仑在宫腔镜手术中的应用研究[J].中国医药科学,2025,15(5):159-162,4.基金项目
广西壮族自治区卫生健康委员会自筹经费科研课题(Z20211211). （Z20211211）
