中国药业2025，Vol.34Issue(7)：16-20,5.DOI:10.3969/j.issn.1006-4931.2025.07.005
慢性阻塞性肺疾病急性加重入院危险因素分析及药学服务模型构建
Construction of the Pharmaceutical Care Model Based on Risk Factors of Admission for Acute Exacerbation of Chronic Obstructive Pulmonary Disease
摘要
Abstract
Objective To improve the quality of pharmaceutical care for patients admitted with acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods A total of 142 COPD patients who established resident health records in Wuyou,Xianfeng and Haiyue Community Health Service Centers in Yancheng,Jiangsu Province from January to December 2023 were selected,and they were divided into the admission group(65 cases)and the non-admission group(77 cases)based on whether the patients were admitted due to acute exacerbation of COPD(AECOPD)in the previous year.Basic information such as gender,age,comorbidities,body mass index(BMI),COPD duration,eosinophil percentage(EOS%),hypoalbuminemia,as well as frequency of AECOPD in the previous year,medication compliance,number of combined drugs,and correct use of inhaled drugs were collected.Univariate analysis and multivariate Logistic regression analysis were used to analyze the risk factors of admission for AECOPD patients within the previous year,and the pharmaceutical care model was constructed.Results Univariate analysis showed that the BMI,disease duration,EOS%,hypoalbuminemia,correct use of inhaled drugs,medication adherence,and number of combined drugs between the two groups were significantly different(P<0.05).Multivariate Logistic regression analysis showed that BMI(≤24 kg/m2),EOS%≥2%,hypoproteinemia(<35 g/L)and incorrect use of inhaled drugs were independent risk factors of admission for AECOPD patients within one year(P<0.05).Based on these independent risk factors,patients were divided into high-risk,medium-risk,and low-risk groups,and a standardized pharmaceutical care model was constructed from the aspects of follow-up frequency,follow-up implementers,and specific follow-up content.Conclusion Based on the high-risk factors of admission for AECOPD patients,rapid screening of high-risk groups and targeted implementation of refined pharmaceutical care can greatly improve the efficiency and quality of pharmaceutical care for AECOPD patients.关键词
慢性阻塞性肺疾病急性加重/入院危险因素/药学服务Key words
acute exacerbation of chronic obstructive pulmonary disease/risk factors of admission/pharmaceutical care分类
医药卫生引用本文复制引用
王阿明,黄磊,张琳琳,石爱平,常晓敏..慢性阻塞性肺疾病急性加重入院危险因素分析及药学服务模型构建[J].中国药业,2025,34(7):16-20,5.基金项目
江苏省药学会-恒瑞医院药学基金科研项目[H202148]. （）
