摘要
Abstract
Objective:To analyze the effect of budesonide inhalation,azithromycin sequential therapy combined with Chinese medicine acupoint application in children with mycoplasma pneumonia(MPP).Method:A total of 116 children with MPP treated in Putian Hanjiang Hospital from January 2020 to October 2023 were selected as the study objects,and were divided into control group and observation group according to random number table method,with 58 cases in each group.The control group was given budesonide suspension aerosol inhalation plus azithromycin sequential therapy.On the basis of control group,the observation group was given Chinese medicine acupoint application.The clinical efficacy,symptom disappearance time,inflammatory index,pulmonary function index and adverse reaction were compared between the two groups.Result:The total effective rate of the observation group after treatment was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).The disappearance time of all symptoms was shorter than that of control group,and the difference was statistically significant(P<0.05).The levels of C-reactive protein(CRP),serum soluble interleukin-2 receptor(sIL-2R),Granulocyte Stimulating Factor(G-CSF)and forced vital capacity(FVC)were lower than those of control group,Forced Respiratory Volume in One Second(FEV1)and Peak Expiratory Flow(PEF)were higher than those of control group,and the difference was statistically significant(P<0.05).There was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion:Chinese medicine acupoint application combined with budesonide atomization inhalation and azithromycin sequential therapy in the treatment of MPP children can enhance the curative effect,accelerate the time of symptom disappearance,reduce the inflammatory response of the body,improve the level of lung function,and have high drug safety.关键词
支原体肺炎/布地奈德/阿奇霉素序贯疗法/疗效/炎症指标/肺功能Key words
Mycoplasma pneumonia/Budesonide/Azithromycin sequential therapy/Therapeutic effect/Inflammatory markers/Pulmonary function
