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通窍活血汤加减治疗急性脑梗死的效果及对炎症和血清Lp-PLA2的影响

于佳卫 李贝贝 马立 屠明锋

中外医学研究2025,Vol.23Issue(9):145-148,4.
中外医学研究2025,Vol.23Issue(9):145-148,4.DOI:10.14033/j.cnki.cfmr.2025.09.039

通窍活血汤加减治疗急性脑梗死的效果及对炎症和血清Lp-PLA2的影响

The Effect of Modified Tongqiao Huoxue Decoction in the Treatment of Acute Cerebral Infarction and Its Influence on Inflammation and Serum Lp-PLA2

于佳卫 1李贝贝 1马立 1屠明锋1

作者信息

  • 1. 溧阳市中医医院 江苏 溧阳 213300
  • 折叠

摘要

Abstract

Objective:To explore the effect of modified Tongqiao Huoxue decoction in the treatment of acute cerebral infarction and its influence on inflammation and lipoprotein-associated phospholipase A2(Lp-PLA2).Method:A total of 120 patients diagnosed with ACI admitted to the Department of Neurology,Liyang Hospital of Chinese Medicine from February 2022 to January 2024 were included in the study,and were divided into control group and observation group according to computer random number table method,with 60 cases in each group.The control group was treated with conventional western medicine,while the observation group was treated with Tongqi Huoxue decoction on the basis of the control group.Laboratory indicators(serum and inflammatory factor levels),clinical efficacy,and adverse reactions were compared between the two groups.Result:There was no difference in serum,inflammatory factors,and TCM symptom scores before treatment between the two groups(P>0.05).After treatment,all indicators in the two groups were lower than those before treatment,and the indicators in the observation group were lower than those in the control group(P<0.05).The curative effect of the traditional Chinese medicine group was higher than that of the western medicine group(P<0.05).There was no difference in adverse reactions between the two groups(P>0.05).Conclusion:The application of Tongqi Huoxue decoction combined with Western medicine in the treatment of acute cerebral infarction has a remarkable effect,which can alleviate clinical symptoms,promote blood circulation,reduce inflammation,and have a remarkable therapeutic effect.

关键词

通窍活血汤/急性脑梗死/脂蛋白相关磷脂酶A2/炎症因子

Key words

Tongqiao Huoxue decoction/Acute cerebral infarction/Lipoprotein-associated phospholipase A2/Inflammatory factors

引用本文复制引用

于佳卫,李贝贝,马立,屠明锋..通窍活血汤加减治疗急性脑梗死的效果及对炎症和血清Lp-PLA2的影响[J].中外医学研究,2025,23(9):145-148,4.

中外医学研究

1674-6805

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