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可切除非小细胞肺癌患者围手术期免疫治疗研究进展

雷雨濛 雷静

中外医学研究2025,Vol.23Issue(9):161-166,6.
中外医学研究2025,Vol.23Issue(9):161-166,6.DOI:10.14033/j.cnki.cfmr.2025.09.043

可切除非小细胞肺癌患者围手术期免疫治疗研究进展

Progress of Immunotherapy in Perioperative Patients with Resectable Non-Small Cell Lung Cancer

雷雨濛 1雷静2

作者信息

  • 1. 贵州医科大学附属医院 贵州 贵阳 550000
  • 2. 川北医学院附属医院
  • 折叠

摘要

Abstract

Non-small cell lung cancer(NSCLC)is the main type of lung cancer,and about 30%of NSCLC patients are in the resectable range when diagnosed.However,the long-term prognosis of patients after radical resection is not ideal,and the main reason for the poor long-term prognosis of patients is tumor recurrence and metastasis.In order to improve the long-term prognosis of patients with resectable NSCLC,the comprehensive treatment strategy of radical surgery combined with perioperative radiotherapy and chemotherapy is often used in clinic,but the curative effect is limited.Therefore,the treatment of resectable NSCLC has always been the focus and hotspot of clinical research.In recent years,immune checkpoint inhibitors(ICIs)have been used in the treatment of various advanced malignant tumors and achieved good results.However,the exploration of combined immunotherapy strategies in the context of comprehensive treatment of resectable NSCLC and the toxicity and side effects are still controversial.To this end,this article reviews the studies on perioperative immunotherapy in patients with resectable NSCLC,aiming to provide reference for comprehensive treatment in patients with resectable NSCLC.

关键词

非小细胞肺癌/可切除/围术期/免疫治疗

Key words

Non-small cell lung cancer/Resectable/Perioperative period/Immunotherapy

引用本文复制引用

雷雨濛,雷静..可切除非小细胞肺癌患者围手术期免疫治疗研究进展[J].中外医学研究,2025,23(9):161-166,6.

中外医学研究

1674-6805

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