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Cisplatin induces acute liver injury by triggering caspase-3/GSDME-me diate d cell pyroptosis

Ping-Ping Wu Xiu-Jin Shen Shu-Sen Zheng

Hepatobiliary & Pancreatic Diseases International2025，Vol.24Issue(2)：P.177-187,11.

Hepatobiliary & Pancreatic Diseases International2025，Vol.24Issue(2)：P.177-187,11.DOI:10.1016/j.hbpd.2024.09.010

Cisplatin induces acute liver injury by triggering caspase-3/GSDME-me diate d cell pyroptosis

Ping-Ping Wu ¹Xiu-Jin Shen ²Shu-Sen Zheng³

作者信息

1. Division of Hepatobiliary Pancreatic Surgery,The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China
2. Kidney Disease Center,The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China Key Laboratory of Kidney Disease Prevention and Control Technology,Hangzhou 310003,China
3. Division of Hepatobiliary Pancreatic Surgery,The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China NHC Key Laboratory of Combined Multi-organ Transplantation,The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China
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摘要

关键词

Cisplatin/Pyroptosis/Hepatotoxicity/Gasdermins/GSDME

分类

医药卫生

引用本文复制引用

Ping-Ping Wu,Xiu-Jin Shen,Shu-Sen Zheng..Cisplatin induces acute liver injury by triggering caspase-3/GSDME-me diate d cell pyroptosis[J].Hepatobiliary & Pancreatic Diseases International,2025,24(2):P.177-187,11.

基金项目

supported by grants from the National Natural Science Foundation of China(8170060495 and 82170682)。（8170060495 and 82170682）

Hepatobiliary & Pancreatic Diseases International

ISSN：1499-3872

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