首页|期刊导航|Neural Regeneration Research|Chitosan alleviates symptoms of Parkinson''''s disease by reducing acetate levels, which decreases inflammation and promotes repair of the intestinal barrier and blood–brain barrier

Chitosan alleviates symptoms of Parkinson''''s disease by reducing acetate levels, which decreases inflammation and promotes repair of the intestinal barrier and blood–brain barrier

Yinying Wang Rongsha Chen Guolin Shi Xinwei Huang Ke Li Ruohua Wang Xia Cao Zhongshan Yang Ninghui Zhao Jinyuan Yan

Neural Regeneration Research2026，Vol.21Issue(1)：P.377-391,15.

Neural Regeneration Research2026，Vol.21Issue(1)：P.377-391,15.DOI:10.4103/NRR.NRR-D-23-01511

Chitosan alleviates symptoms of Parkinson''''s disease by reducing acetate levels, which decreases inflammation and promotes repair of the intestinal barrier and blood–brain barrier

Yinying Wang ¹Rongsha Chen ²Guolin Shi ³Xinwei Huang ²Ke Li ²Ruohua Wang ²Xia Cao ²Zhongshan Yang ⁴Ninghui Zhao ³Jinyuan Yan²

作者信息

1. Central Laboratory,The Second Affiliated Hospital of Kunming Medical University,Kunming,Yunnan Province,China Yunnan Provincial Key Laboratory of Molecular Biology for Sino Medicine,Yunnan University of Chinese Medicine,Kunming,Yunnan Province,China
2. Central Laboratory,The Second Affiliated Hospital of Kunming Medical University,Kunming,Yunnan Province,China
3. Department of Neurosurgery,The Second Affiliated Hospital of Kunming Medical University,Kunming,Yunnan Province,China
4. Yunnan Provincial Key Laboratory of Molecular Biology for Sino Medicine,Yunnan University of Chinese Medicine,Kunming,Yunnan Province,China
折叠

摘要

关键词

acetate/adenosine 5′-monophosphate-activated protein kinase/blood–brain barrier/chitosan/dopamine neurons/inflammation/intestinal barrier/Parkinson''s disease/peroxisome proliferator-activated receptor delta/short-chain fatty acids

分类

医药卫生

引用本文复制引用

Yinying Wang,Rongsha Chen,Guolin Shi,Xinwei Huang,Ke Li,Ruohua Wang,Xia Cao,Zhongshan Yang,Ninghui Zhao,Jinyuan Yan..Chitosan alleviates symptoms of Parkinson''''s disease by reducing acetate levels, which decreases inflammation and promotes repair of the intestinal barrier and blood–brain barrier[J].Neural Regeneration Research,2026,21(1):P.377-391,15.

基金项目

supported by the National Natural Science Foundation of China,Nos. 32260196 (to JY), 81860646 (to ZY) and 31860274 (to JY) （to JY）

a grant from Yunnan Department of Science and Technology,Nos. 202101AT070251 (to JY), 202201AS070084 (to ZY), 202301AY070001-239 (to JY), 202101AZ070001-012, and 2019FI016 (to ZY)。（to JY）

Neural Regeneration Research

ISSN：1673-5374

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