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Synaptic and synchronic impairments in subcortical brain regions associated with early non-cognitive dysfunction in Alzheimer''''s disease

Nicolás Riffo-Lepe Juliana González-Sanmiguel Lorena Armijo-Weingart Paulina Saavedra-Sieyes David Hernandez Gerson Ramos Loreto S.San Martín Luis G.Aguayo

Neural Regeneration Research2026，Vol.21Issue(1)：P.248-264,17.

Neural Regeneration Research2026，Vol.21Issue(1)：P.248-264,17.DOI:10.4103/NRR.NRR-D-24-01052

Synaptic and synchronic impairments in subcortical brain regions associated with early non-cognitive dysfunction in Alzheimer''''s disease

Nicolás Riffo-Lepe ¹Juliana González-Sanmiguel ¹Lorena Armijo-Weingart ²Paulina Saavedra-Sieyes ¹David Hernandez ¹Gerson Ramos ¹Loreto S.San Martín ³Luis G.Aguayo³

作者信息

1. Laboratorio de Neurofisiología,Departamento de Fisiología,Universidad de Concepción,Concepción,Chile
2. Facultad de Odontología y Ciencias de la Rehabilitación,Universidad San Sebastián,Concepción,Chile
3. Laboratorio de Neurofisiología,Departamento de Fisiología,Universidad de Concepción,Concepción,Chile Programa de Neurociencia,Psiquiatría y Salud Mental(NEPSAM),Universidad de Concepción,Concepción,Chile
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摘要

关键词

Alzheimer''s disease/AMPA receptors/amygdala/epilepsy/gamma-aminobutyric acid/glutamate/hippocampus/neurodegeneration/neuronal excitability/N-methyl-D-aspartate receptors/non-cognitive/nucleus accumbens

分类

医药卫生

引用本文复制引用

Nicolás Riffo-Lepe,Juliana González-Sanmiguel,Lorena Armijo-Weingart,Paulina Saavedra-Sieyes,David Hernandez,Gerson Ramos,Loreto S.San Martín,Luis G.Aguayo..Synaptic and synchronic impairments in subcortical brain regions associated with early non-cognitive dysfunction in Alzheimer''''s disease[J].Neural Regeneration Research,2026,21(1):P.248-264,17.

基金项目

supported by ANID/CONICYT Fondecyt Regular 1221080(to LGA) （to LGA）

Fondecyt Postdoctoral fellow 3210260(to LAW) （to LAW）

ANID PhD fellowship 21202521(to NRL) （to NRL）

21211228(to JGS) （to JGS）

21211758(to PSS)and 21230078(to DH)。（to PSS）

Neural Regeneration Research

ISSN：1673-5374

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