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首页|期刊导航|Neural Regeneration Research|Targeting the glymphatic system to promoteα-synuclein clearance:a novel therapeutic strategy for Parkinson's disease

Targeting the glymphatic system to promoteα-synuclein clearance:a novel therapeutic strategy for Parkinson's disease

Xiaoyue Lian Zhenghao Liu Zuobin Gan Qingshan Yan Luyao Tong Linan Qiu Yuntao Liu Jiang-fan Chen Zhihui Li

Neural Regeneration Research2026,Vol.21Issue(1):P.233-247,15.
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Neural Regeneration Research2026,Vol.21Issue(1):P.233-247,15.DOI:10.4103/NRR.NRR-D-24-00764

Targeting the glymphatic system to promoteα-synuclein clearance:a novel therapeutic strategy for Parkinson's disease

Xiaoyue Lian 1Zhenghao Liu 1Zuobin Gan 1Qingshan Yan 1Luyao Tong 1Linan Qiu 2Yuntao Liu 1Jiang-fan Chen 2Zhihui Li2

作者信息

  • 1. Molecular Neuropharmacology Laboratory and Eye-Brain Research Center,State Key Laboratory of Ophthalmology,Optometry and Vision Science,School of Ophthalmology&Optometry and Eye Hospital,Wenzhou Medical University,Wenzhou,Zhejiang Province,China
  • 2. Molecular Neuropharmacology Laboratory and Eye-Brain Research Center,State Key Laboratory of Ophthalmology,Optometry and Vision Science,School of Ophthalmology&Optometry and Eye Hospital,Wenzhou Medical University,Wenzhou,Zhejiang Province,China Oujiang Laboratory(Zhejiang Laboratory for Regenerative Medicine,Vision and Brain Health),School of Ophthalmology&Optometry and Eye Hospital,Wenzhou Medical University,Wenzhou,Zhejiang Province,China
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摘要

关键词

aquaporin-4/astrocytes/cerebrospinal fluid/glymphatic system/interstitial fluid/neurotoxic protein clearance/Parkinson''s disease/perivascular spaces/sleep disturbance/α-synuclein

分类

医药卫生

引用本文复制引用

Xiaoyue Lian,Zhenghao Liu,Zuobin Gan,Qingshan Yan,Luyao Tong,Linan Qiu,Yuntao Liu,Jiang-fan Chen,Zhihui Li..Targeting the glymphatic system to promoteα-synuclein clearance:a novel therapeutic strategy for Parkinson's disease[J].Neural Regeneration Research,2026,21(1):P.233-247,15.

基金项目

supported by the National Natural Science Foundation of China,No.81971031(to ZL) (to ZL)

the National Key Research and Development Program of China,No.2022YFE0210100(to JFC) (to JFC)

the National Natural Science Foundation of China(Original Exploration Project),No.82151308(to JFC) (Original Exploration Project)

the National Natural Science Foundation of China(Research Fund for International Senior Scientists),No.82150710558(to JFC) (Research Fund for International Senior Scientists)

Science&Technology Initiative STI2030-Major Projects,No.2021ZD0203400(to JFC) (to JFC)

Key Research and Development Program of Zhejiang Province,No.2023C03079(to JFC) (to JFC)

Scientific Research Starting Foundation of Oujiang Laboratory(Zhejiang Laboratory for Regenerative Medicine,Vision and Brain Health),No.OJQDSP2022007(to JFC) (Zhejiang Laboratory for Regenerative Medicine,Vision and Brain Health)

Project of State Key Laboratory of Ophthalmology,Optometry and Visual Science,Wenzhou Medical University,No.J01-20190101(to JFC) (to JFC)

Scientific Research Starting Foundation of Wenzhou Medical University,No.QTJ12003(to JFC) (to JFC)

Department of Science and Technology of Zhejiang Province,No.2023ZY1011(to JFC)。 (to JFC)

Neural Regeneration Research

1673-5374

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