磁共振成像2025，Vol.16Issue(3)：38-43,6.DOI:10.12015/issn.1674-8034.2025.03.006
两种三维磁共振神经成像技术对鼻咽癌患者下颌神经颅外段显示效果的对比研究
Comparative study on the display effect of two three-dimensional magnetic resonance neuroimaging techniques on mandibular nerve extracranial segment in patients with nasopharyngeal carcinoma
摘要
Abstract
Objective:To compare the feasibility and value of three-dimensional double echo steady state(3D-DESS)sequence and three-dimensional flip-angle evolution short-tau inversion(3D-SPACE-STIR)sequence in the display of mandibular nerve extracranial segment in patients with nasopharyngeal carcinoma.Materials and Methods:The image data of 36 patients with nasopharyngeal carcinoma meeting the inclusion and exclusion criteria were retrospectively analyzed,with a total of 72 mandibular nerves.The paired sample t test and paired sample Wilcoxon sign rank sum test were used to compare the subjective scores and objective parameters of the display quality of the two sequences,including the signal intensity ratio(SIR),signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)of the images.Paired Chi-square test was used to compare the mandibular nerve involvement between the two sequences in nasopharyngeal carcinoma.Results:Both 3D-DESS and 3D-SPACE-STIR sequences had a higher display rate of mandibular nerve,and the subjective quality scores of both showed a good performance,which were 4 and 3 points,respectively,with no statistical significance(P=0.052);3D-SPACE-STIR sequence SIRN/M was better than 3D-DESS sequence,3.55 and 1.40,respectively,and the difference was statistically significant(P<0.001).SNRM of 3D-DESS sequence was better than that of 3D-SPACE-STIR sequence(13.68 and 8.00,respectively),and the difference was statistically significant(P=0.002).A total of 24 mandibular nerves were involved by tumors.3D-DESS sequences showed better relationship between nerves and tumors(95.83%vs.12.50%),nerve continuity(87.50%vs.37.50%)and nerve morphology(70.83%vs.29.17%)of tumor segments than 3D-SPACE-STIR sequences,and the differences were statistically significant(P<0.001,P<0.001,P=0.004).The 3D-SPACE-STIR sequence showed that the nerve thickening in non-tumor segment was better than that in 3D-DESS sequence(70.83%vs.41.67%),and the difference was statistically significant(P=0.042).Conclusions:3D-DESS and 3D-SPACE-STIR have similar display rates on the extracranial segment of mandibular nerve,but 3D-DESS is based on better resolution of the relationship between nerve and surrounding structure and low field of view value,and its clinical application is worthy of promotion.关键词
三维双回波稳态进动序列/三维短时反转恢复快速自旋回波成像序列/下颌神经/磁共振成像/鼻咽癌/脑神经Key words
three-dimensional double echo steady state/three-dimensional flip-angle evolution short-tau inversion/mandibular nerve/magnetic resonance imaging/nasopharynx cancer/cranial nerves分类
医药卫生引用本文复制引用
罗江静,徐列印,胡玉芳,唐艳云..两种三维磁共振神经成像技术对鼻咽癌患者下颌神经颅外段显示效果的对比研究[J].磁共振成像,2025,16(3):38-43,6.基金项目
Guilin Science and Technology Plan Project(No.20230135-3-3) （No.20230135-3-3）
Guilin Medical College Young and Middle-Aged Faculty Research Ability Enhancement Project(No.2018glmcy065) （No.2018glmcy065）
Health Commission of Guangxi Province Self-Funded Research Project(No.Z20190755). 桂林市科技计划项目(编号:20230135-3-3) （No.Z20190755）
桂林医学院中青年教职工科研能力提升项目(编号:2018glmcy065) （编号:2018glmcy065）
广西壮族自治区卫生健康委员会自筹经费科研课题项目(编号:Z20190755) （编号:Z20190755）
