磁共振成像2025，Vol.16Issue(3)：122-126,5.DOI:10.12015/issn.1674-8034.2025.03.020
定量磁化率成像技术在帕金森病中的研究进展
Research progress of quantitative susceptibility mapping in Parkinson's disease
摘要
Abstract
Parkinson's disease(PD)is a late-onset neurodegenerative disorder with an increasing incidence year by year.The dysregulation of iron homeostasis in the brain is regarded as one of the significant pathological features of PD.In recent years,remarkable progress has been made in the field of neuroimaging,which has opened up new vistas for the clinical diagnosis of PD and the in-depth exploration of its pathological mechanisms.Against this backdrop,quantitative susceptibility mapping(QSM)technology,as an advanced magnetic resonance imaging modality,utilizes the phase information in magnetic resonance imaging to achieve an accurate quantitative assessment of iron content in brain tissue.This paper reviews the imaging principle of QSM technology and its potential value and application prospects in the diagnosis of PD,aiming to provide new insights for PD diagnosis.关键词
帕金森病/定量磁化率成像/磁共振成像/铁沉积Key words
Parkinson's disease/quantitative susceptibility mapping/magnetic resonance imaging/iron deposition分类
医药卫生引用本文复制引用
石玥,董林菘,陈绍华,李洪义,杜禹辛,魏秀芳..定量磁化率成像技术在帕金森病中的研究进展[J].磁共振成像,2025,16(3):122-126,5.基金项目
Key Research and Development Program of Heilongjiang Province(No.SC2024ZX12C0036) （No.SC2024ZX12C0036）
Scientific Research Project of the Basic Scientific Research Operating Expenses for Provincial Colleges and Universities in Heilongjiang Province(No.2023-KYYWFMY-0014). 黑龙江省重点研发计划项目(编号:SC2024ZX12C0036) （No.2023-KYYWFMY-0014）
黑龙江省省属高等学校基本科研业务费科研项目(编号:2023-KYYWFMY-0014) （编号:2023-KYYWFMY-0014）
