磁共振成像2025，Vol.16Issue(3)：190-195,6.DOI:10.12015/issn.1674-8034.2025.03.032
磁共振弹性成像在慢性肝脏疾病中的应用进展
Advancements and applications of magnetic resonance elastography in chronic liver diseases
摘要
Abstract
Chronic liver disease exhibits a high prevalence worldwide and often progresses to liver fibrosis or cirrhosis,leading to severe complications such as liver failure and hepatocellular carcinoma.Early diagnosis and staging of liver fibrosis are crucial for the management of chronic liver disease.In recent years,magnetic resonance elastography(MRE)has emerged as a vital tool for liver fibrosis assessment due to its non-invasive nature and high accuracy.With continuous advancements in MRE technology,its application in evaluating liver fibrosis in chronic liver disease has significantly expanded.Initially,MRE was primarily used for liver fibrosis assessment in common etiologies such as viral hepatitis and metabolic dysfunction-associated fatty liver disease.However,with technological progress and increasing clinical demand,MRE has gradually been applied to a broader range of etiologies,including alcohol related-liver disease and autoimmune liver diseases.Furthermore,the application of MRE in assessing the progression of hepatitis and liver fibrosis,monitoring treatment efficacy,and predicting clinical outcomes has been extensively studied.These advancements have not only expanded the clinical utility of MRE but also provided essential imaging support for the individualized management of chronic liver diseases with diverse etiologies.Based on the different etiologies and common complications of chronic liver disease,this review summarizes the latest progress in the use of MRE for the evaluation of chronic liver disease,aiming to offer valuable insights for its clinical management.关键词
磁共振弹性成像/慢性肝脏疾病/肝纤维化/生物力学特性参数Key words
magnetic resonance elastography/chronic liver diseases/liver fibrosis/mechanobiological properties分类
临床医学引用本文复制引用
蒋卓儒,张海龙,朱正阳,张鑫,张冰,李婕,陈俊..磁共振弹性成像在慢性肝脏疾病中的应用进展[J].磁共振成像,2025,16(3):190-195,6.基金项目
National Science and Technology Major Project(No.2023ZD0508802) （No.2023ZD0508802）
National Natural Science Foundation of China(No.82170609,81970545) （No.82170609,81970545）
NSFC-RGC Young Scholars Forum Project of National Natural Science Foundation of China(No.82411560273),Natural Science Foundation of Jiangsu Province(No.BK20231118). 国家科技重大专项(编号:2023ZD0508802) （No.82411560273）
国家自然科学基金项目(编号:82170609、81970545) （编号:82170609、81970545）
国家自然科学基金NSFC-RGC青年学者论坛项目(编号:82411560273),江苏省自然科学基金项目(编号:BK20231118) （编号:82411560273）
